EP 0000053 A1 19781220 - Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them.
Title (en)
Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them.
Title (de)
Somatostatin-ähnliche Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.
Title (fr)
Analogues de la somatostatine, procédé pour leur préparation et des compositions pharmaceutiques les contenant.
Publication
Application
Priority
US 80467877 A 19770608
Abstract (en)
[origin: US4146612A] Somatostatin analogs having the structural formula: <CHEM> wherein A is Phe, Tyr, O-Me-Tyr, B is Phe, Tyr, C is Thr, Val, wherein the ring formed by the peptide backbone contains 26 atoms and pharmaceutically acceptable non-toxic acid addition salts thereof are prepared by the solid phase method. These peptides have the property of inhibiting release of insulin, inhibiting growth hormone release and inhibiting glucagon release in humans and animals without materially affecting gastric secretion.
IPC 1-7
IPC 8 full level
A61K 38/04 (2006.01); A61P 3/02 (2006.01); C07K 7/56 (2006.01); C07K 1/113 (2006.01); C07K 14/575 (2006.01); C07K 14/655 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP US)
A61P 3/02 (2018.01 - EP); C07K 14/6555 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); Y10S 930/16 (2013.01 - EP)
Citation (search report)
- DE 2460469 A1 19760701 - HOECHST AG
- [P] FR 2336943 A1 19770729 - AYERST MCKENNA & HARRISON [CA]
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000053 A1 19781220; EP 0000053 B1 19810527; DE 2860734 D1 19810903; DK 252778 A 19781209; IE 47421 B1 19840307; IE 781151 L 19781208; IT 1105131 B 19851028; IT 7849736 A0 19780606; JP S543085 A 19790111; US 4146612 A 19790327
DOCDB simple family (application)
EP 78100095 A 19780606; DE 2860734 T 19780606; DK 252778 A 19780607; IE 115178 A 19780606; IT 4973678 A 19780606; JP 6872378 A 19780607; US 92052978 A 19780629