EP 0000074 B1 19800806 - NEW BISPIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM
Title (en)
NEW BISPIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM
Publication
Application
Priority
DE 2726571 A 19770613
Abstract (en)
[origin: US4183935A] Bispidine derivatives of the formula <IMAGE> where R1 is H or C6H5, R2 is H, Cl or CF3, R3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzylpiperid-4-one with appropriately substituted phenylalkylamines, followed by reduction. They exhibit mainly anti-arrhythmic action.
IPC 1-7
IPC 8 full level
A61K 31/435 (2006.01); A61K 31/445 (2006.01); A61P 9/06 (2006.01); C07D 471/08 (2006.01); C07D 221/00 (2006.01)
CPC (source: EP US)
A61P 9/06 (2017.12 - EP); C07D 471/08 (2013.01 - EP US)
Designated contracting state (EPC)
BE CH DE FR GB NL SE
DOCDB simple family (publication)
EP 0000074 A1 19781220; EP 0000074 B1 19800806; AT 363937 B 19810910; AT A426578 A 19810215; CA 1105023 A 19810714; DE 2726571 A1 19781221; DE 2860111 D1 19801127; FI 63403 B 19830228; FI 63403 C 19830610; FI 781872 A 19781214; JP S5412398 A 19790130; US 4183935 A 19800115
DOCDB simple family (application)
EP 78100147 A 19780613; AT 426578 A 19780612; CA 305369 A 19780613; DE 2726571 A 19770613; DE 2860111 T 19780613; FI 781872 A 19780612; JP 6837578 A 19780608; US 91511978 A 19780613