EP 0000152 A1 19790110 - Oxaminic acids and esters, process for their preparation and pharmaceutical compositions containing them.
Title (en)
Oxaminic acids and esters, process for their preparation and pharmaceutical compositions containing them.
Title (de)
Oxamin-Säuren und Ester hiervon, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Gemische.
Title (fr)
Acides et esters oxaminiques, procédés pour leur préparation et compositions pharmaceutiques les contenant.
Publication
Application
Priority
- CH 791377 A 19770628
- CH 791477 A 19770628
Abstract (en)
Compounds of the formula: <CHEM> wherein R1 is hydrogen or alkyl of 1 to 10 carbon atoms, R2 is chlorine or alkoxy of 1 to 4 carbon atoms, or R1 and R2 together are -(CH2)m- wherein m is 3 or 4 and R3 is OH or alkoxy of 1 to 4 carbon atoms are prepared. <??>The compounds are obtained by acylation of the amino derivative with an oxalic-esters derivative. Hydrolysis of the oxamic ester gives the oxamic acid. <??>The compounds are useful for the treatment of allergic conditions.
IPC 1-7
IPC 8 full level
A61K 31/195 (2006.01); A61K 31/215 (2006.01); A61K 31/22 (2006.01); A61P 43/00 (2006.01); C07C 233/00 (2006.01); A61K 31/19 (2006.01); C07C 233/33 (2006.01)
CPC (source: EP US)
A61P 43/00 (2018.01 - EP); C07C 233/00 (2013.01 - EP US)
Citation (search report)
[A] US 2589934 A 19520318 - GLENN HOWARD J, et al
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000152 A1 19790110; EP 0000152 B1 19810909; AU 3746978 A 19800103; AU 519473 B2 19811203; CA 1130307 A 19820824; DE 2861051 D1 19811126; DK 275378 A 19781229; FI 781946 A 19781229; IE 47627 B1 19840516; IE 781272 L 19781228; IL 55006 A0 19780831; IL 55006 A 19811130; IT 1097293 B 19850831; IT 7825028 A0 19780627; JP S5412360 A 19790130; NZ 187677 A 19810123; PH 14995 A 19820322; PT 68216 A 19780701; US 4148916 A 19790410
DOCDB simple family (application)
EP 78100167 A 19780615; AU 3746978 A 19780626; CA 306275 A 19780627; DE 2861051 T 19780615; DK 275378 A 19780619; FI 781946 A 19780619; IE 127278 A 19780626; IL 5500678 A 19780626; IT 2502878 A 19780627; JP 7708478 A 19780627; NZ 18767778 A 19780626; PH 21307 A 19780626; PT 6821678 A 19780626; US 91794978 A 19780622