Global Patent Index - EP 0000252 A1

EP 0000252 A1 19790110 - Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides.

Title (en)

Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides.

Title (de)

Peptiden, Verfahren zu dessen Herstellung und denen enthaltende pharmazeutische Präparate.

Title (fr)

Peptides, compositions pharmaceutiques les contenant et procédé de préparation de ces peptides.

Publication

EP 0000252 A1 19790110 (EN)

Application

EP 78300046 A 19780615

Priority

GB 2714077 A 19770629

Abstract (en)

[origin: ES471243A1] Peptides (6-12 amino acids) and their salts, useful in allergy desensitization compositions, particularly vaccines, have the formula X-R-R1-R2-R3-Y where R is optional and, if present, is a group resistant to enzyme hydrolysis R1 is a basic amino acid residue optionally linked to basic and/or neutral nonhydrophobic amino acid residues R2 is one or more neutral nonhydrophobic amino acid residues R3 is one or more hydrophobic amino acid residues optionally linked to neutral nonhydrophobic amino acid residues X is hydrogen or an N-protecting group and Y is hydroxyl or a C-terminal protecting group. Examples are: Lys Thr Lys Gly Ser Gly Phe Phe OCH3 Arg Lys Thr Lys Gly Ser Gly Phe Phe OCH3 Lys Thr Lys Gly Ser Gly Phe Phe Val Phe OCH3 Lys Thr Lys Gly Ser Gly Phe Phe Val Phe OH Pro Arg Lys Thr Lys Gly Ser Gly Phe Phe OCH3 Lys Thr Lys Gly Ser Gly Phe Phe OH

IPC 1-7

C07C 103/52; A61K 37/02

IPC 8 full level

A61K 38/00 (2006.01); A61P 37/00 (2006.01); C07K 5/06 (2006.01); C07K 5/083 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 16/06 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP US)

A61P 37/00 (2018.01 - EP); C07K 5/06052 (2013.01 - EP US); C07K 5/06069 (2013.01 - EP US); C07K 5/0806 (2013.01 - EP US); C07K 5/1013 (2013.01 - EP US); C07K 7/06 (2013.01 - EP US); C07K 7/08 (2013.01 - EP US); C07K 16/065 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US); Y02P 20/55 (2015.11 - EP US); Y10S 930/32 (2013.01 - EP US)

Citation (search report)

  • [A] FR 2257304 A1 19750808 - BECTON DICKINSON CO [US]
  • [X] PETTIT "Synthetic peptides", 1971, Edit. Reinhold CO., Vol. 2, New York. Page 102.
  • [X] CHEMICAL ABSTRACTS vol. 72, nr. 67261r (1970) & Vest Mosk Univ Khim, 1969, 24 (6), 113
  • [X] CHEMICAL ABSTRACTS, vol. 80, nr. 48404p (1974) & JP-A-48 076 817 (Kurihara)
  • [X] CHEMICAL ABSTRACTS, vol. 77, nr. 20028h (1972) & HU-A-3841 (Gyogyszerkutato Int.)
  • CHEMICAL ABSTRACTS, vol. 83, nr. 43727y (1975) & J. Biol. Chem. 1975 250 (5), 1912-18
  • CHEMICAL ABSTRACTS, vol. 82, nr. 112240c (1975) & Endocrinol. Gut 1973 103-6

Designated contracting state (EPC)

BE CH DE FR GB LU NL SE

DOCDB simple family (publication)

EP 0000252 A1 19790110; EP 0000252 B1 19820203; AU 3762878 A 19800103; AU 522641 B2 19820617; CA 1105006 A 19810714; DE 2861593 D1 19820311; DK 292778 A 19781230; ES 471243 A1 19791001; IE 47105 B1 19831228; IE 781290 L 19781229; IL 54967 A0 19780831; IL 54967 A 19820331; IT 7850095 A0 19780629; JP S5416402 A 19790207; NZ 187638 A 19810713; US 4223016 A 19800916; ZA 783699 B 19790627

DOCDB simple family (application)

EP 78300046 A 19780615; AU 3762878 A 19780629; CA 306411 A 19780628; DE 2861593 T 19780615; DK 292778 A 19780628; ES 471243 A 19780628; IE 129078 A 19780628; IL 5496778 A 19780621; IT 5009578 A 19780629; JP 7920678 A 19780629; NZ 18763878 A 19780621; US 92015178 A 19780629; ZA 783699 A 19780628