EP 0000285 B1 19820217 - 7-ACYLAMINO-3-((3-(CARBOXYMETHYL) THIO-1 H-1,2,4-TRIAZOL-5-YL) THIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
Title (en)
7-ACYLAMINO-3-((3-(CARBOXYMETHYL) THIO-1 H-1,2,4-TRIAZOL-5-YL) THIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
Publication
Application
Priority
US 81164277 A 19770630
Abstract (en)
[origin: US4117124A] Cephalosporins of the formula <CHEM> in which R represents various acyl substituents; R min represents hydrogen or an alkali metal salt, have anti-bacterial activity. They can be prepared by reacting 4,5-dihydro-5- thioxo-1H- 1,2,4- triazol-3-yl thioacetic acid or an alkali metal salt thereof with the corresponding 3-acetoxymethyl cephalosporin. The thioacetic acids used as intermediates in preparing cephalosporins of the invention are also part of the present invention.
IPC 1-7
IPC 8 full level
A61K 31/545 (2006.01); A61K 31/546 (2006.01); A61P 31/04 (2006.01); C07D 249/12 (2006.01); C07D 501/36 (2006.01)
CPC (source: EP US)
A61P 31/04 (2017.12 - EP); C07D 249/12 (2013.01 - EP US)
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
US 4117124 A 19780926; DE 2861631 D1 19820325; DE 2862354 D1 19840112; EP 0000285 A1 19790110; EP 0000285 B1 19820217; EP 0015631 A1 19800917; EP 0015631 B1 19831207; JP S5412396 A 19790130; JP S6054958 B2 19851203
DOCDB simple family (application)
US 81164277 A 19770630; DE 2861631 T 19780629; DE 2862354 T 19780629; EP 78300103 A 19780629; EP 80200247 A 19780629; JP 7796778 A 19780626