EP 0000299 B1 19801112 - NOVEL DERIVATIVES OF SUBSTITUTED 2-BENZOYL-4-CHLORO-GLYCINANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES.
Title (en)
NOVEL DERIVATIVES OF SUBSTITUTED 2-BENZOYL-4-CHLORO-GLYCINANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES.
Publication
Application
Priority
FR 7718511 A 19770616
Abstract (en)
[origin: ES470861A1] The invention relates to new substituted 2-benzoyl-4-chloroglycinanilide derivatives, to a process for their production and to their use as medicaments. The new derivatives according to the invention correspond to the general formula < IMAGE > (I) in which: R may be a linear or branched alkyl group, preferably a lower alkyl group R1 and R2 may be the same or different and are selected from hydrogen, alkyl, alkenyl, alkynyl, hydroxy alkyl, alkoxy alkyl and aralkyl groups, these various groups optionally being linear or branched, and from 3- to 6-membered cycloalkyl groups optionally substituted on the alpha -carbon atom by an alkynyl radical in addition, the groups R1 and R2 may form with the nitrogen atom to which they are attached an optionally saturated 5-membered or 6-membered nitrogen heterocycle optionally containing a second heteroatom selected from oxygen and nitrogen, said heterocycle optionally being substituted, preferably on the second nitrogen atom, by a lower alkyl radical and their salts obtained with therapeutically acceptable mineral or organic acids.
IPC 1-7
C07C 103/50; C07D 295/14; C07D 233/60; A61K 31/16; A61K 31/395
IPC 8 full level
A61K 31/165 (2006.01); A61K 31/34 (2006.01); A61K 31/341 (2006.01); A61P 25/00 (2006.01); A61P 25/20 (2006.01); A61K 31/195 (2006.01); C07C 237/04 (2006.01); C07C 237/06 (2006.01); C07C 273/10 (2006.01); C07D 233/56 (2006.01); C07D 295/15 (2006.01); C07D 307/52 (2006.01)
CPC (source: EP US)
A61P 25/00 (2018.01 - EP); A61P 25/20 (2018.01 - EP); C07D 295/15 (2013.01 - EP US)
Designated contracting state (EPC)
BE CH DE FR GB NL
DOCDB simple family (publication)
EP 0000299 A1 19790110; EP 0000299 B1 19801112; CA 1124256 A 19820525; DE 2860270 D1 19810205; ES 470861 A1 19790201; FR 2403330 A1 19790413; FR 2403330 B1 19821105; IT 1156820 B 19870204; IT 7849859 A0 19780614; JP S5436238 A 19790316; US 4372975 A 19830208; ZA 783410 B 19790627
DOCDB simple family (application)
EP 78400009 A 19780601; CA 305549 A 19780615; DE 2860270 T 19780601; ES 470861 A 19780616; FR 7718511 A 19770616; IT 4985978 A 19780614; JP 7314178 A 19780616; US 20062280 A 19801027; ZA 783410 A 19780614