EP 0000300 B1 19820106 - SUBSTITUTED ESTRA-1,3,5(10),6-TETRAENES, PROCESS FOR THEIR PREPARATION AND USE IN THE SYNTHESIS OF TRITIUM LABELLED STEROIDS
Title (en)
SUBSTITUTED ESTRA-1,3,5(10),6-TETRAENES, PROCESS FOR THEIR PREPARATION AND USE IN THE SYNTHESIS OF TRITIUM LABELLED STEROIDS
Publication
Application
Priority
FR 7719613 A 19770627
Abstract (en)
[origin: US4191697A] Novel DELTA 1,3,5(10),6-estratetraenes of the formula <IMAGE> I R is selected from the group consisting of hydrogen, acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl and R1 is selected from the group consisting of acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl, novel intermediates therefore, process for the preparation of estradiols marked with a tritium atom and the novel tritiated estradiols which are useful to the study and dosage of specific receptors of estrogen.
IPC 1-7
IPC 8 full level
A61K 51/00 (2006.01); C07J 1/00 (2006.01); C07J 17/00 (2006.01); C07J 51/00 (2006.01); G01N 33/534 (2006.01); G01N 33/60 (2006.01)
CPC (source: EP US)
C07J 1/007 (2013.01 - EP US)
Designated contracting state (EPC)
BE CH DE GB NL SE
DOCDB simple family (publication)
EP 0000300 A1 19790110; EP 0000300 B1 19820106; CA 1130277 A 19820824; DE 2861501 D1 19820225; FR 2401173 A1 19790323; FR 2401173 B1 19800404; IT 1105060 B 19851028; IT 7850022 A0 19780626; JP S5412362 A 19790130; JP S62142196 A 19870625; JP S6220196 B2 19870506; JP S6360035 B2 19881122; US 4191697 A 19800304
DOCDB simple family (application)
EP 78400016 A 19780612; CA 306095 A 19780623; DE 2861501 T 19780612; FR 7719613 A 19770627; IT 5002278 A 19780626; JP 28221186 A 19861128; JP 7660378 A 19780626; US 91560178 A 19780615