EP 0000526 B1 19801112 - PHARMACEUTICAL PREPARATIONS CONTAINING PENICILLINS OR CEPHALOSPORINS AND CLAVULANIC ACID; PROCESS FOR THEIR PREPARATION
Title (en)
PHARMACEUTICAL PREPARATIONS CONTAINING PENICILLINS OR CEPHALOSPORINS AND CLAVULANIC ACID; PROCESS FOR THEIR PREPARATION
Publication
Application
Priority
DE 2733642 A 19770726
Abstract (en)
[origin: EP0000526A1] 1. An antibiotic composition, characterised in that it contains an active compound combination consisting of (1) beta-lactam antibiotics of the formula I : see diagramm : EP0000526,P9,F1 in which R1 represents see diagramm : EP0000526,P9,F2 see diagramm : EP0000526,P9,F3 see diagramm : EP0000526,P9,F4 see diagramm : EP0000526,P9,F5 see diagramm : EP0000526,P9,F6 and see diagramm : EP0000526,P9,F7 R2 represents phenyl, p-hydroxyphenyl or furyl, R3 represents H, OCH3 or OC2 H5 and wherein Y denotes see diagramm : EP0000526,P9,F8 or see diagramm : EP0000526,P9,F9 wherein T represents -O-CO-CH3 , -O-CO-NH2 , see diagramm : EP0000526,P9,F10 see diagramm : EP0000526,P9,F11 or see diagramm : EP0000526,P9,F12 and R4 is H, CH3 , -CH2 -COOH, -CH2 -SO3 H or -CH2 -CH2 -N(CH3 )2 or their pharmaceutically usable salts, in particular the sodium salts, or their various crystal or hydrate forms and (2) clavulanic acid of the formula II see diagramm : EP0000526,P9,F13 or its pharmaceutically usable salts or esters which can be split vivo, in particular its sodium salt.
IPC 1-7
IPC 8 full level
A61K 31/43 (2006.01); A61K 31/545 (2006.01); A61P 31/04 (2006.01); A61K 31/42 (2006.01)
CPC (source: EP)
A61K 31/43 (2013.01); A61K 31/545 (2013.01); A61P 31/04 (2018.01); C10M 2201/02 (2013.01); C10M 2209/103 (2013.01); C10M 2209/104 (2013.01); C10M 2219/044 (2013.01); C10N 2020/01 (2020.05); C10N 2040/20 (2013.01)
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000526 A1 19790207; EP 0000526 B1 19801112; AT 361618 B 19810325; AT A534478 A 19800815; DE 2733642 A1 19790208; DE 2860275 D1 19810205; DK 330478 A 19790302; ES 471984 A1 19791016; IL 55206 A0 19780929; IL 55206 A 19811231; IT 1097330 B 19850831; IT 7826041 A0 19780724; JP S5435219 A 19790315
DOCDB simple family (application)
EP 78100407 A 19780717; AT 534478 A 19780724; DE 2733642 A 19770726; DE 2860275 T 19780717; DK 330478 A 19780725; ES 471984 A 19780724; IL 5520678 A 19780724; IT 2604178 A 19780724; JP 8953678 A 19780724