EP 0000538 A1 19790207 - 6,7-Dihydro-5H,13H-quinazolino(3,2-a)(1,4)benzodiazepine-5,13-diones, process for their preparation and their use as medicaments.
Title (en)
6,7-Dihydro-5H,13H-quinazolino(3,2-a)(1,4)benzodiazepine-5,13-diones, process for their preparation and their use as medicaments.
Title (de)
6,7-Dihydro-5H,13H-chinazolino(3,2-a)(1,4)benzodiazepin-5,13-dione, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel.
Title (fr)
6,7-Dihydro-5H,13H-quinazolino(3,2-a) (1,4)benzodiazépine-5,13-diones, procédé pour leur préparation et leur application comme médicaments.
Publication
Application
Priority
- DE 2733681 A 19770726
- DE 2758875 A 19771230
Abstract (en)
[origin: ES471985A1] The invention covers compounds of the formula < IMAGE > in which R1 and R5 each represents 0, 1, 2, 3 or 4 of the following substituents: alkyl, hydroxyl, acyloxy, alkoxy, nitro, amino, alkylamino, dialkylamino, acylamino, acylalkylamino, alkoxycarbonylamino, halogen, trifluoromethyl, cyano, carboxyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminosulphonyl, alkylaminosulphonyl, dialkylaminoamino, R2 is hydrogen, optionally substituted alkyl, aralkyl or aryl or heterocyclo-alkyl, acyl or alkoxycarbonyl, and R3 and R4 are each hydrogen, or optionally substituted alkyl, aralkyl, aryl or hetero-aryl, are useful as medicaments which have an action on the central nervous system, in particular as, for example, tranquilizers and/or antiamnesics. Also included in the invention are methods for preparing said compounds, compositions containing them and methods for the use of said compounds and compositions.
IPC 1-7
IPC 8 full level
A61K 31/55 (2006.01); A61P 25/04 (2006.01); A61P 25/20 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); C07D 239/91 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61P 25/04 (2017.12 - EP); A61P 25/20 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); C07D 239/91 (2013.01 - EP US); C07D 487/04 (2013.01 - EP US)
Citation (search report)
[A] US 3280117 A 19661018 - GRIOT RUDOLF G
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000538 A1 19790207; AU 3828478 A 19800131; DK 330378 A 19790127; ES 471985 A1 19791001; FI 782318 A 19790127; IL 55207 A0 19780929; IT 7826042 A0 19780724; JP S5424896 A 19790224; US 4187306 A 19800205
DOCDB simple family (application)
EP 78100425 A 19780718; AU 3828478 A 19780724; DK 330378 A 19780725; ES 471985 A 19780724; FI 782318 A 19780724; IL 5520778 A 19780724; IT 2604278 A 19780724; JP 8953778 A 19780724; US 92241978 A 19780706