Global Patent Index - EP 0000644 A2

EP 0000644 A2 19790207 - Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions.

Title (en)

Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions.

Title (de)

Mit niedrigen Cycloalkylresten substituierte Benzolderivate, Verfahren zu ihrer Herstellung, sowie ihre pharmazeutischen Zusammensetzungen.

Title (fr)

Dérivés de benzène substitué par un radical cycloalkyle inférieur, procédé de préparation et leurs compositions pharmaceutiques.

Publication

EP 0000644 A2 19790207 (EN)

Application

EP 78300168 A 19780719

Priority

GB 3022977 A 19770719

Abstract (en)

Lower cycloalkyl substituted-benzene derivatives of the formula:- <CHEM> wherein R<1> is lower cycloalkyl, R<2> is carboxy, esterified carboxy, hydroxymethyl, lower alkoxymethyl or acyloxymethyl, R<3> is lower alkanoyl or lower alkyl substituted with hydroxy, amino, lower alkylamino, di(lower)alkylamino, acylamino, lower alkoxy, acyl or acyloxy, in which the lower alkyl moieties of the di(lower)alkyl amino radical may be joined together to form a heterocyclic ring containing the nitrogen atom and the carbonyl function of the acyl radical, which is a substituent on the lower alkyl radical, may be protected, X is hydrogen or halogen, and Y is a valency bond or lower alkylene; and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising the same; and methods for treatment of inflammation by administering the same to mammals.

IPC 1-7

C07C 65/20; A61K 31/00; C07C 31/34; C07C 43/12; C07C 65/14; C07C 69/76; C07C 91/16; C07C 101/04; C07C 101/18; C07C 143/74; C07C 143/822

IPC 8 full level

A61K 31/12 (2006.01); A61K 31/19 (2006.01); A61K 31/21 (2006.01); A61K 31/357 (2006.01); A61K 31/445 (2006.01); A61P 29/00 (2006.01); C07C 27/00 (2006.01); C07C 29/14 (2006.01); C07C 29/147 (2006.01); C07C 33/50 (2006.01); C07C 41/26 (2006.01); C07C 43/168 (2006.01); C07C 43/178 (2006.01); C07C 45/00 (2006.01); C07C 45/59 (2006.01); C07C 49/252 (2006.01); C07C 57/48 (2006.01); A61K 31/335 (2006.01); C07C 59/56 (2006.01); C07C 59/72 (2006.01); C07C 67/00 (2006.01); C07C 69/157 (2006.01); C07C 69/732 (2006.01); C07C 69/734 (2006.01); C07C 69/738 (2006.01); C07C 215/38 (2006.01); C07C 217/48 (2006.01); C07C 227/00 (2006.01); C07C 229/34 (2006.01); C07C 229/36 (2006.01); C07C 233/05 (2006.01); C07C 233/13 (2006.01); C07C 233/18 (2006.01); C07C 233/31 (2006.01); C07C 233/47 (2006.01); C07C 233/87 (2006.01); C07C 275/24 (2006.01); C07C 301/00 (2006.01); C07C 309/73 (2006.01); C07C 311/03 (2006.01); C07C 311/04 (2006.01); C07D 213/80 (2006.01); C07D 295/145 (2006.01); C07D 317/30 (2006.01)

CPC (source: EP)

A61P 29/00 (2018.01); C07C 29/14 (2013.01); C07C 33/50 (2013.01); C07C 41/16 (2013.01); C07C 41/18 (2013.01); C07C 41/26 (2013.01); C07C 43/168 (2013.01); C07C 43/1788 (2013.01); C07C 45/59 (2013.01); C07C 49/252 (2013.01); C07C 57/48 (2013.01); C07C 59/56 (2013.01); C07C 59/72 (2013.01); C07C 69/734 (2013.01); C07C 309/73 (2013.01); C07C 311/04 (2013.01); C07D 213/80 (2013.01); C07D 295/145 (2013.01); C07D 317/30 (2013.01); C07C 2601/14 (2017.05)

C-Set (source: EP)

  1. C07C 45/59 + C07C 49/252
  2. C07C 41/18 + C07C 43/168
  3. C07C 41/26 + C07C 43/1788
  4. C07C 41/16 + C07C 43/1788
  5. C07C 29/14 + C07C 33/50

Designated contracting state (EPC)

BE CH DE FR GB LU NL SE

DOCDB simple family (publication)

EP 0000644 A2 19790207; EP 0000644 A3 19790919; IT 1109502 B 19851216; IT 7825878 A0 19780719; JP S5422348 A 19790220; JP S6141333 B2 19860913

DOCDB simple family (application)

EP 78300168 A 19780719; IT 2587878 A 19780719; JP 8888278 A 19780719