Global Patent Index - EP 0000656 A1

EP 0000656 A1 19790207 - 4"-Ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions.

Title (en)

4"-Ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions.

Title (de)

4"Ureido-Oleandomycinderivate, Verfahen zu ihrer Herstellung und ihre Verwendung in Arzneimitteln.

Title (fr)

Dérivés du 4"-uréido-oléandomycine, procédé pour leur préparation et leur emploi dans des compositions pharmaceutiques.

Publication

EP 0000656 A1 19790207 (EN)

Application

EP 78300186 A 19780724

Priority

US 81890777 A 19770725

Abstract (en)

[origin: US4098993A] A compound of the formula: <CHEM> wherein Y is a group of the formula: -NHCONHR1, <CHEM> -N = C = O or -NHCN; R is alkanoyl having two or three carbon atoms; R1 is hydrogen, pyridylmethyl, furylmethyl, thenyl, hydroxypyridyl, phenyl, benzyl, or phenyl or benzyl substituted by methyl, chloro, fluoro, methoxy, amino or trifluoromethyl; and X is methyl, methoxy, fluoro, chloro or trifluoromethyl; or a pharmaceutically acceptable acid addition salt thereof when Y is other than -N = C = O. A process for preparing these compounds and pharmaceutical compositions containing them.

IPC 1-7

C07H 17/08; A61K 31/70

IPC 8 full level

A61K 31/70 (2006.01); A61K 31/7042 (2006.01); A61K 31/7048 (2006.01); A61P 31/04 (2006.01); C07H 17/08 (2006.01)

CPC (source: EP US)

A61P 31/04 (2018.01 - EP); C07H 17/08 (2013.01 - EP US)

Citation (search report)

[AD] US 3022219 A 19620220 - CELMER WALTER D

Designated contracting state (EPC)

BE DE FR GB LU NL

DOCDB simple family (publication)

US 4098993 A 19780704; DE 2860469 D1 19810326; DK 329078 A 19790126; EP 0000656 A1 19790207; EP 0000656 B1 19810211; IE 47714 B1 19840530; IE 781467 L 19790125; IT 1097329 B 19850831; IT 7826036 A0 19780724; JP S5424887 A 19790224; JP S5463094 A 19790521; JP S5463095 A 19790521; JP S5628919 B2 19810704; JP S564560 B2 19810130; JP S5715120 B2 19820329

DOCDB simple family (application)

US 81890777 A 19770725; DE 2860469 T 19780724; DK 329078 A 19780724; EP 78300186 A 19780724; IE 146778 A 19780721; IT 2603678 A 19780724; JP 9031678 A 19780724; JP 9031778 A 19780724; JP 9031878 A 19780724