EP 0000716 B1 19830309 - PYRROLO(2,1-B)(3)BENZAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (en)
PYRROLO(2,1-B)(3)BENZAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Publication
Application
Priority
US 81973977 A 19770728
Abstract (en)
[origin: EP0000716A2] Compounds of formula: <CHEM> wherein X and Y are hydrogen, halogen, trifluoromethyl, alkyl, alkoxy, cyano, trifluoromethylthio, or trifluoromethyl sulfonyl; and R is alkyl or cyclopropylmethyl, and the dotted line represents saturation or unsaturation, have utility as antipsychotic agents. They also demonstrate antiserotonin and antihistaminic activity. They are prepared by reaction of a pyrrolo (2, 1-b) (3) benzazepin-11-one with a piperidinyl magnesium halide followed by dehydration.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61P 25/18 (2006.01); A61P 43/00 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61P 25/18 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 487/04 (2013.01 - EP US)
Citation (examination)
- US 3014911 A 19611226 - ENGELHARDT EDWARD L
- US 3988342 A 19761026 - PRUGH JOHN D
- US 4031222 A 19770621 - REMY DAVID C
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000716 A2 19790221; EP 0000716 A3 19790516; EP 0000716 B1 19830309; DE 2862196 D1 19830414; DK 328478 A 19790129; IE 47146 B1 19831228; IE 781517 L 19790128; IT 1107463 B 19851125; IT 7850403 A0 19780720; JP S5427597 A 19790301; US 4148903 A 19790410
DOCDB simple family (application)
EP 78100454 A 19780720; DE 2862196 T 19780720; DK 328478 A 19780724; IE 151778 A 19780727; IT 5040378 A 19780720; JP 9167378 A 19780728; US 81973977 A 19770728