EP 0000718 B1 19820324 - QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS AND THEIR PREPARATION
Title (en)
QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS AND THEIR PREPARATION
Publication
Application
Priority
- CH 577678 A 19780526
- LU 77829 A 19770725
Abstract (en)
[origin: US4256748A] Compounds of the formula <IMAGE> I wherein R1,R2,R3 and R4 are as hereinafter described, tautomers and salts thereof, are disclosed. The foregoing compounds inhibit the aggregation of blood platelets which renders them useful as therapeutic agents in the prophylaxis of thromboses. Furthermore, they are useful for the treatment and prophylaxis of cardiac insufficiency and cardiac failure, due to their inotropic activity without substantial tachycardia.
IPC 1-7
IPC 8 full level
A61K 31/505 (2006.01); A61P 7/02 (2006.01); A61P 9/04 (2006.01); C07D 233/68 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61P 7/02 (2018.01 - EP); A61P 9/04 (2018.01 - EP); C07D 487/04 (2013.01 - EP US)
Designated contracting state (EPC)
BE CH DE FR LU NL SE
DOCDB simple family (publication)
US 4256748 A 19810317; AR 218500 A1 19800613; AT 363479 B 19810810; AT A535178 A 19810115; AU 3812778 A 19800124; AU 519688 B2 19811217; BR 7804763 A 19790410; CA 1094555 A 19810127; CS 203014 B2 19810227; DE 2832138 A1 19790208; DE 2861688 D1 19820429; DK 144128 B 19811214; DK 144128 C 19820517; DK 328978 A 19790126; EP 0000718 A2 19790221; EP 0000718 A3 19790613; EP 0000718 B1 19820324; ES 471981 A1 19791016; ES 476955 A1 19791016; FI 63409 B 19830228; FI 63409 C 19830610; FI 782248 A 19790126; FR 2398748 A1 19790223; FR 2398748 B1 19810904; GB 2001638 A 19790207; GB 2001638 B 19820210; GR 72968 B 19840120; HU 177643 B 19811128; IE 47280 B1 19840208; IE 781478 L 19790125; IL 55183 A0 19780929; IL 55183 A 19811130; IT 1097337 B 19850831; IT 7826019 A0 19780724; JP S5441894 A 19790403; MC 1199 A1 19790319; MY 8500249 A 19851231; NL 7807507 A 19790129; NO 150800 B 19840910; NO 150800 C 19841227; NO 782541 L 19790126; NZ 187921 A 19810316; PH 14642 A 19811012; PT 68342 A 19780801; SE 7808111 L 19790126; YU 177578 A 19830121
DOCDB simple family (application)
US 5039579 A 19790620; AR 27306478 A 19780725; AT 535178 A 19780724; AU 3812778 A 19780718; BR 7804763 A 19780724; CA 307767 A 19780720; CS 491478 A 19780724; DE 2832138 A 19780721; DE 2861688 T 19780721; DK 328978 A 19780724; EP 78100471 A 19780721; ES 471981 A 19780724; ES 476955 A 19790118; FI 782248 A 19780714; FR 7821396 A 19780719; GB 7830868 A 19780724; GR 780156847 A 19780724; HU HO002088 A 19780719; IE 147878 A 19780724; IL 5518378 A 19780720; IT 2601978 A 19780724; JP 8953478 A 19780724; MC 1312 A 19780713; MY 8500249 A 19851230; NL 7807507 A 19780712; NO 782541 A 19780724; NZ 18792178 A 19780720; PH 21412 A 19780721; PT 6834278 A 19780724; SE 7808111 A 19780724; YU 177578 A 19780725