EP 0000741 A3 19790307 - INDOLACETOXY ACETYLAMINO ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DRUGS
Title (en)
INDOLACETOXY ACETYLAMINO ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DRUGS
Publication
Application
Priority
DE 2735537 A 19770806
Abstract (en)
[origin: EP0000741A2] 1. Indolylacetoxyacetylaminoacetic acid derivatives of the general formula (I) see diagramm : EP0000741,P17,F3 in which m and n represent the numbers 0 or 1, X represents a -NH- or -OCH2 - group, R1 , R2 and R3 are identical or different and each represent hydrogen, an alkyl with 1 to 5 carbon atoms optionally substituted by hydroxy, alkoxy with 1 to 4 carbon atoms, alkylthio with 1 to 4 carbon atoms or by phenylalkoxycarbonylamino with 1 to 4 carbon atoms in the alkyl part, or represents a phenyl or phenylalkyl group with 1 to 4 carbon atoms in the alkyl part, the phenyl rings optionally being substituted by trifluoromethyl, alkoxy with 1 to 4 carbon atoms, hydroxy or halogen or represents a heterocyclic methyl group with 5 to 6 ring members, in which 1 or 2 members can be replaced by nitrogen and to which a benzene ring is optionally fused, or in the case where m and n each represent 0, R1 additionally represents an amino group, an alkoxycarbonylamino group or a phenylalkoxycarbonylamino group with in each case 1 to 5 carbon atoms in the alkoxy part, R4 represents hydroxy, alkoxy with 1 to 4 carbon atoms, phenalkoxy with 1 to 4 carbon atoms in the alkoxy part, amino, alkylamino with 1 to 4 carbon atoms in the alkyl part, benzylamino or phenylamino, and their physiologically acceptable salts appropriately formed with acids and bases.
IPC 1-7
IPC 8 full level
A61K 31/405 (2006.01); A61K 38/00 (2006.01); C07D 209/44 (2006.01); A61P 29/00 (2006.01); C07D 209/28 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/08 (2006.01); C07K 5/083 (2006.01); C07K 5/09 (2006.01)
CPC (source: EP)
A61P 29/00 (2018.01); C07D 209/28 (2013.01); C07K 5/06078 (2013.01); C07K 5/0806 (2013.01); C07K 5/0815 (2013.01)
Citation (search report)
- [D] DE 2413125 A1 19751009 - SCHERING AG
- [D] FR 2192828 A1 19740215 - TROPONWERKE DINKLAGE & CO [DE]
Designated contracting state (EPC)
BE CH DE FR GB NL
DOCDB simple family (publication)
EP 0000741 A2 19790221; EP 0000741 A3 19790307; EP 0000741 B1 19810722; DE 2735537 A1 19790222; DE 2860858 D1 19811029; IT 7826537 A0 19780804; JP S5430160 A 19790306
DOCDB simple family (application)
EP 78100523 A 19780727; DE 2735537 A 19770806; DE 2860858 T 19780727; IT 2653778 A 19780804; JP 9469878 A 19780804