EP 0000741 B1 19810722 - INDOLACETOXYACETYLAMINOACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DRUGS
Title (en)
INDOLACETOXYACETYLAMINOACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DRUGS
Publication
Application
Priority
DE 2735537 A 19770806
Abstract (en)
[origin: EP0000741A2] 1. Indolylacetoxyacetylaminoacetic acid derivatives of the general formula (I) see diagramm : EP0000741,P17,F3 in which m and n represent the numbers 0 or 1, X represents a -NH- or -OCH2 - group, R1 , R2 and R3 are identical or different and each represent hydrogen, an alkyl with 1 to 5 carbon atoms optionally substituted by hydroxy, alkoxy with 1 to 4 carbon atoms, alkylthio with 1 to 4 carbon atoms or by phenylalkoxycarbonylamino with 1 to 4 carbon atoms in the alkyl part, or represents a phenyl or phenylalkyl group with 1 to 4 carbon atoms in the alkyl part, the phenyl rings optionally being substituted by trifluoromethyl, alkoxy with 1 to 4 carbon atoms, hydroxy or halogen or represents a heterocyclic methyl group with 5 to 6 ring members, in which 1 or 2 members can be replaced by nitrogen and to which a benzene ring is optionally fused, or in the case where m and n each represent 0, R1 additionally represents an amino group, an alkoxycarbonylamino group or a phenylalkoxycarbonylamino group with in each case 1 to 5 carbon atoms in the alkoxy part, R4 represents hydroxy, alkoxy with 1 to 4 carbon atoms, phenalkoxy with 1 to 4 carbon atoms in the alkoxy part, amino, alkylamino with 1 to 4 carbon atoms in the alkyl part, benzylamino or phenylamino, and their physiologically acceptable salts appropriately formed with acids and bases.
IPC 1-7
IPC 8 full level
A61K 31/405 (2006.01); A61K 38/00 (2006.01); C07D 209/44 (2006.01); A61P 29/00 (2006.01); C07D 209/28 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/08 (2006.01); C07K 5/083 (2006.01); C07K 5/09 (2006.01)
CPC (source: EP)
A61P 29/00 (2018.01); C07D 209/28 (2013.01); C07K 5/06078 (2013.01); C07K 5/0806 (2013.01); C07K 5/0815 (2013.01)
Designated contracting state (EPC)
BE CH DE FR GB NL
DOCDB simple family (publication)
EP 0000741 A2 19790221; EP 0000741 A3 19790307; EP 0000741 B1 19810722; DE 2735537 A1 19790222; DE 2860858 D1 19811029; IT 7826537 A0 19780804; JP S5430160 A 19790306
DOCDB simple family (application)
EP 78100523 A 19780727; DE 2735537 A 19770806; DE 2860858 T 19780727; IT 2653778 A 19780804; JP 9469878 A 19780804