EP 0000931 A1 19790307 - Enzymatic cleavage of N-acyl-thienamycins.
Title (en)
Enzymatic cleavage of N-acyl-thienamycins.
Title (de)
Enzymatische Spaltung von N-acyl-Thienamycinen.
Title (fr)
Rupture enzymatique de N-acyl-thiénamycines.
Publication
Application
Priority
US 82588377 A 19770819
Abstract (en)
A method is disclosed for cleaving N-acylthienamycin compounds to yield thienamycin. The new method disclosed herein utilizes enzymes which are penicillin amidohydrolases to treat the starting compounds resulting in the antibiotic thienamycin.
IPC 1-7
IPC 8 full level
C07D 477/20 (2006.01); C12P 17/18 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP US)
C07D 477/20 (2013.01 - EP US)
Citation (search report)
- [X] DE 2652678 A1 19770602 - MERCK & CO INC
- [A] US 3260653 A 19660712 - WILFRIED KAUFMANN, et al
- [A] NL 7800958 A 19780815 - MERCK & CO INC
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0000931 A1 19790307; EP 0000931 B1 19820414; DE 2861737 D1 19820527; DK 365478 A 19790220; ES 472701 A1 19790216; IE 47315 B1 19840222; IE 781674 L 19790219; IT 1106626 B 19851111; IT 7850747 A0 19780816; JP S5446890 A 19790413; JP S6210639 B2 19870307; PT 68428 A 19780901; US 4162193 A 19790724
DOCDB simple family (application)
EP 78100699 A 19780818; DE 2861737 T 19780818; DK 365478 A 19780818; ES 472701 A 19780818; IE 167478 A 19780818; IT 5074778 A 19780816; JP 10046478 A 19780819; PT 6842878 A 19780816; US 82588377 A 19770819