EP 0000972 A3 19790321 - 2-SUBSTITUTED-3-PHENYLINDOLES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (en)
2-SUBSTITUTED-3-PHENYLINDOLES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Publication
Application
Priority
US 82835577 A 19770829
Abstract (en)
[origin: EP0000972A2] The invention relates to novel 3-phenyl-indoles of the formula <CHEM> wherein X and Y are independently hydrogen or halogen atoms; each n is 1, 2 or 3, Q is an oxygen atom or the group (H,OH), Z is a hydrogen atom, or provided that Q is an oxygen atom, Z can also be the group OR, wherein R is a hydrogen atom or a lower alkyl or loweralkoxy-loweralkyl group, "lower" indicating groups with 1-6 carbon atoms, m is 1 or 2 when Z is a hydrogen atom and m is O when Z is the group OR, to their preparation, and to pharmaceutical compositions containing them. These compounds have immunosuppressant activity and can be used for example in the treatment of rheumatoid arthritis.
IPC 1-7
IPC 8 full level
A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61P 37/00 (2006.01); C07D 209/12 (2006.01)
CPC (source: EP)
A61P 37/00 (2018.01); C07C 251/72 (2013.01); C07D 209/12 (2013.01)
Citation (search report)
- DE 1966206 A1 19720120 - SUMITOMO CHEMICAL CO [JP]
- JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 86, 1964, pages 1639-1640
- JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 85, 1963, pages 3410-3414
Designated contracting state (EPC)
BE CH DE FR GB NL SE
DOCDB simple family (publication)
EP 0000972 A2 19790307; EP 0000972 A3 19790321; AU 3921578 A 19800228; DK 373278 A 19790301; FI 782587 A 19790301; IT 1098266 B 19850907; IT 7826921 A0 19780822; JP S5446777 A 19790412; ZA 784856 B 19790829
DOCDB simple family (application)
EP 78200153 A 19780823; AU 3921578 A 19780824; DK 373278 A 19780824; FI 782587 A 19780824; IT 2692178 A 19780822; JP 10333978 A 19780824; ZA 784856 A 19780825