EP 0001627 B1 19840404 - 3-SUBSTITUTED-6-(1'HYDROXETHYL)-7-OXO-1-AZABICYCLO(3.2.0.)-HEPT-2-ENE-2-CARBOXYLIC ACID, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
Title (en)
3-SUBSTITUTED-6-(1'HYDROXETHYL)-7-OXO-1-AZABICYCLO(3.2.0.)-HEPT-2-ENE-2-CARBOXYLIC ACID, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
Publication
Application
Priority
US 84337577 A 19771019
Abstract (en)
[origin: EP0001627A1] Disclosed are 3-substituted-6-(1 min -hydroxyethyl)-7-oxo-1-azabicyclo [3.2.0] hept-2-ene -2-carboxylic acids having the structure: <CHEM> wherein R<x> is, inter alia, selected from the group consisting of hydrogen, alkyl, alkenyl, aryl and aralkyl. Such compounds as well as their pharmaceutically acceptable 0- and carboxyl derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
IPC 1-7
IPC 8 full level
A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61P 31/04 (2006.01); C07C 205/42 (2006.01); C07D 205/08 (2006.01); C07D 477/00 (2006.01); C07D 477/20 (2006.01); C07D 477/26 (2006.01); C07D 498/04 (2006.01); C07F 7/10 (2006.01)
CPC (source: EP)
A61P 31/04 (2018.01); C07C 205/42 (2013.01); C07D 205/08 (2013.01); C07D 477/20 (2013.01); C07D 477/26 (2013.01); C07F 7/10 (2013.01)
Citation (examination)
EP 0001628 A1 19790502 - MERCK & CO INC [US]
Designated contracting state (EPC)
BE CH DE FR GB LU NL SE
DOCDB simple family (publication)
EP 0001627 A1 19790502; EP 0001627 B1 19840404; AU 4061378 A 19800417; DE 2862395 D1 19840510; DK 464478 A 19790420; ES 474289 A1 19791101; IT 1110867 B 19860106; IT 7851566 A0 19781018; JP H0438753 B2 19920625; JP S5466696 A 19790529; ZA 785857 B 19800625
DOCDB simple family (application)
EP 78101156 A 19781016; AU 4061378 A 19781011; DE 2862395 T 19781016; DK 464478 A 19781018; ES 474289 A 19781017; IT 5156678 A 19781018; JP 12792678 A 19781019; ZA 785857 A 19781018