EP 0028246 A4 19820329 - CONTROLLED PROTEIN FRACTIONATION.
Title (en)
CONTROLLED PROTEIN FRACTIONATION.
Title (de)
GESTEUERTE PROTEIN-FRAKTIONIERUNG.
Title (fr)
FRACTIONNEMENT CONTROLE DES PROTEINES.
Publication
Application
Priority
US 3603179 A 19790504
Abstract (en)
[origin: WO8002380A1] A controlled protein fractionation method in which a cold protein-containing solution is circulated in contact with one side of a membrane and the temperature is controlled by circulating a protein precipitant solution in contact with the opposite side of the membrane. The flow rate is increased and back pressure is exerted on the precipitant solution to cause it to penetrate the membrane, mix with the protein solution and precipitate protein in fine particles along an inside membrane wall. The precipitated protein may be concentrated and separated by centrifugation or diafiltration. The membrane is preferably in the form of a plurality of hollow fibers. Control of process variables increases yield and purity, decreases processing time and reduces degree of denaturization. The method is especially applicable to carrying out the Cohn cold alcohol fractionation process.
IPC 1-7
IPC 8 full level
C07K 1/30 (2006.01); C07K 1/34 (2006.01); C07K 14/00 (2006.01); B01D 21/01 (2006.01); C07K 14/435 (2006.01); C07K 14/76 (2006.01); C07K 14/765 (2006.01)
CPC (source: EP)
B01D 61/00 (2013.01); B01D 61/145 (2013.01); C07K 1/30 (2013.01); C07K 14/765 (2013.01); B01D 2311/04 (2013.01); B01D 2311/10 (2013.01)
C-Set (source: EP)
Citation (search report)
- US 4142966 A 19790306 - PERRY ELI
- FR 2380362 A2 19780908 - BAXTER TRAVENOL LAB [US]
- US 4218312 A 19800819 - PERRY ELI [US]
- GB 2001755 A 19790207 - FRESENIUS EDUARD DR
- FR 2285398 A1 19760416 - BLUTSENPENDEDIENST LANDESVERBA [DE]
- FR 2265686 A1 19751024 - MONSANTO CO [US]
- FR 2323427 A1 19770408 - GAMBRO AG [CH]
- GB 1583015 A 19810121 - BAXTER TRAVENOL LAB
- FR 2394086 A1 19790105 - FRESENIUS CHEM PHARM IND [DE]
- FR 2333546 A1 19770701 - MONSANTO CO [US]
- GB 1559874 A 19800130 - EXTRACORPOREAL MED SPEC
- US 4066549 A 19780103 - OESER HENNING, et al
Designated contracting state (EPC)
AT CH DE FR GB LU NL SE
DOCDB simple family (publication)
WO 8002380 A1 19801113; AR 224765 A1 19820115; BE 883099 A 19801103; CA 1161368 A 19840131; DK 537380 A 19801217; EP 0028246 A1 19810513; EP 0028246 A4 19820329; ES 491138 A0 19810516; ES 8107244 A1 19810516; FI 801439 A 19801105; FR 2455608 A1 19801128; GR 68187 B 19811109; IL 59975 A0 19800731; IL 59975 A 19830731; IT 1131137 B 19860618; IT 8021790 A0 19800502; JP S56500442 A 19810409; NO 803951 L 19801229; NZ 193605 A 19830510; PT 71179 A 19800701; PT 71179 B 19820620; ZA 802667 B 19810624
DOCDB simple family (application)
US 8000481 W 19800501; AR 28088780 A 19800502; BE 6047155 A 19800502; CA 351044 A 19800501; DK 537380 A 19801217; EP 80901060 A 19801117; ES 491138 A 19800502; FI 801439 A 19800505; FR 8009775 A 19800430; GR 800161811 A 19800429; IL 5997580 A 19800501; IT 2179080 A 19800502; JP 50127480 A 19800501; NO 803951 A 19801229; NZ 19360580 A 19800502; PT 7117980 A 19800502; ZA 802667 A 19800502