EP 0029567 A1 19810603 - Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionamide compositions.
Title (en)
Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionamide compositions.
Title (de)
Herstellung von Cyanacetamid und 2,2-Dibromo-3-nitrilpropionamid-Zusammensetzungen.
Title (fr)
Préparation du cyanoacétamide et de compositions contenant du dibromo-2,2 nitrilo-3 propanamide.
Publication
Application
Priority
US 9746879 A 19791126
Abstract (en)
[origin: US4328171A] An alkyl alpha -cyanoacetate is reacted with ammonia in a glycol solvent medium to form cyanoacetamide. Advantageously and without requirement of separation of the formed cyanoacetamide in glycol solvent (even though the next step and entire procedure can optionally commence with pre-formed cyanoacetamide), 2,2-dibromo-3-nitrilopropionamide is formed in situ by treating the cyanoacetamide in glycol with an appropriate mixture of bromine and an alkali metal bromate at about 10 DEG C-40 DEG C. Excellent and stable antimicrobial compositions may then be prepared, as part of an overall integrated process by incorporating in the resultant 2,2-dibromo-3-nitrilopropionamide-containing reaction mass an appropriate quantity of paraformaldehyde or equivalent satisfactory stabilizer at a suitably adjusted pH level.
IPC 1-7
IPC 8 full level
A01N 37/34 (2006.01); C07C 67/00 (2006.01); C07C 253/00 (2006.01); C07C 253/30 (2006.01); C07C 255/27 (2006.01)
CPC (source: EP US)
A01N 37/34 (2013.01 - EP US); C07C 255/00 (2013.01 - EP US); Y02P 20/10 (2015.11 - EP US)
Citation (search report)
- DE 2326186 A1 19741212 - DOW CHEMICAL CO
- DE 2538254 A1 19770310 - BASF AG
- AT 265526 B 19681010 - CIBA GEIGY [CH]
- DE 2138278 A1 19720203
- US RE29826 E 19781107
- US 3915685 A 19751028 - KONYA KAZUMI, et al
- CHEMICAL ABSTRACTS, Vol. 48, 1954, Columbus, Ohio,USA M.D. AVASARE, M.L. SHAH and N.M. SHETH " Formation of the iodo derivates of substituted cyanoacetamide and acetoamide ", abstract mo. 5111g & J. Indian Chem. Soc. 29, 709-10 ( 1952 )
Designated contracting state (EPC)
DE FR GB IT NL
DOCDB simple family (publication)
EP 0029567 A1 19810603; EP 0029567 B1 19830323; AU 538159 B2 19840802; AU 6414180 A 19810604; CA 1145360 A 19830426; DE 3062466 D1 19830428; JP H0156062 B2 19891128; JP H02131457 A 19900521; JP H03115204 A 19910516; JP H0325415 B2 19910405; JP H0451521 B2 19920819; JP S5687551 A 19810716; US 4328171 A 19820504
DOCDB simple family (application)
EP 80107124 A 19801117; AU 6414180 A 19801106; CA 363313 A 19801027; DE 3062466 T 19801117; JP 11278889 A 19890501; JP 16650780 A 19801126; JP 24598690 A 19900914; US 9746879 A 19791126