EP 0037814 A1 19811021 - GEL CONTAINING FIBRINE AND ANTIBIOTIC FOR TREATING INFECTED BONES AND PREPARATION PROCESS THEREOF.
Title (en)
GEL CONTAINING FIBRINE AND ANTIBIOTIC FOR TREATING INFECTED BONES AND PREPARATION PROCESS THEREOF.
Title (de)
FIBRIN-ANTIBIOTIKUM-GEL ZUR BEHANDLUNG DES INFIZIERTEN KNOCHENS UND VERFAHREN ZU SEINER HERSTELLUNG.
Title (fr)
GEL CONTENANT FIBRINE ET ANTIBIOTIQUE POUR LE TRAITEMENT D'OS INFECTES ET SON PROCEDE DE PREPARATION.
Publication
Application
Priority
DE 2935194 A 19790831
Abstract (en)
[origin: WO8100516A1] A gel based on fibrine and antibiotic for the treatment of an infected bone contains fibrinogene, a solution containing thrombin and enriched with calcium ions as well as an antibiotic of the tobramycin, gentiamycin group and/or one of their physiologically acceptable salts. The gel may be prepared by mixing the fibrinogene in the form of a lyophilisate or cryoprecipitate with an antibiotic in sterile conditions and then adding a thrombin solution enriched with calcium ions.
Abstract (fr)
Un gel a base de fibrine et d'antibiotique pour le traitement d'un os infecte contient du fibrinogene une solution contenant de la thrombine et enrichie en ions calcium ainsi qu'un antibiotique du groupe tobramycine, gentiamycine et/ou un de leurs sels physiologiquement inoffensifs. Le gel peut etre prepare par melange du fibrinogene sous forme d'un lyophilisat ou d'un cryoprecipite avec un antibiotique dans des conditions steriles puis par adjonction d'une solution de thrombine enrichie en ions calcium.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 31/21 (2006.01); A61K 31/70 (2006.01); A61L 24/00 (2006.01); A61L 26/00 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); A61F 2/00 (2006.01)
CPC (source: EP)
A61K 9/146 (2013.01); A61K 31/21 (2013.01); A61L 24/0031 (2013.01); A61L 26/0042 (2013.01); A61L 27/225 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61F 2310/00377 (2013.01)
Designated contracting state (EPC)
AT CH DE FR GB LI NL SE
DOCDB simple family (publication)
WO 8100516 A1 19810305; EP 0037814 A1 19811021; JP S56501129 A 19810813
DOCDB simple family (application)
EP 8000083 W 19800827; EP 80901723 A 19810309; JP 50205580 A 19800827