EP 0041644 B1 19840912 - SALTS OF 2-HYDROXYMALONATO DIAMMINE PLATINUM (II) COMPOUNDS, PROCESS FOR PREPARING SAID COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS
Title (en)
SALTS OF 2-HYDROXYMALONATO DIAMMINE PLATINUM (II) COMPOUNDS, PROCESS FOR PREPARING SAID COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS
Publication
Application
Priority
- US 15311780 A 19800527
- US 17280580 A 19800728
- US 22732481 A 19810122
Abstract (en)
[origin: EP0041644A2] Disclosed are water-soluble salts of the known antitumor agents 2-hydroxymalonato diammine platinum (II), 2-hydroxymalonato (1,2-diaminocyclohexane)platinum (II) and 2-hydroxymalonato (1,1-diaminomethylcyclohexane)-platinum (II). The novel sodium and ammonium salts of the present invention possess high water-solubility, thus allowing intravenous dosage forms to be prepared for treatment of mammalian tumors.
IPC 1-7
IPC 8 full level
A61K 31/70 (2006.01); A61K 31/7024 (2006.01); A61P 3/06 (2006.01); C07F 15/00 (2006.01); C07H 13/10 (2006.01)
CPC (source: EP US)
A61P 3/06 (2017.12 - EP); C07F 15/0093 (2013.01 - EP); C07H 13/10 (2013.01 - EP US)
Citation (examination)
CHEMICAL ABSTRACTS, volumes 76-85, 1972-1976, NINTH COLLECTIVE INDEX, Index of Ring Systems, Formulas A-C6H10N7O, page 681F, COLUMBUS, OHIO (US), C3H8N2O5Pt, Platinum, diammine-(hydroxypropanedioato(2-)-O1,O3)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0041644 A2 19811216; EP 0041644 A3 19820203; EP 0041644 B1 19840912; AU 538863 B2 19840830; AU 7058881 A 19811203; CA 1173452 A 19840828; DE 3165977 D1 19841018; NZ 197104 A 19840531
DOCDB simple family (application)
EP 81104020 A 19810525; AU 7058881 A 19810514; CA 378325 A 19810526; DE 3165977 T 19810525; NZ 19710481 A 19810514