Global Patent Index - EP 0043608 A1

EP 0043608 A1 19820113 - Hemolytic method for the kinetic determination of antistreptolysin O antibodies in blood or serum samples, using oxidised SO.

Title (en)

Hemolytic method for the kinetic determination of antistreptolysin O antibodies in blood or serum samples, using oxidised SO.

Title (de)

Hämolytisches Verfahren zur kinetischen Bestimmung von Antistreptolysin-O-Antikörpern in Blut- oder Serumproben, unter Anwendung von oxydiertem Streptolysin-O.

Title (fr)

Procédé hémolytique pour la détermination cinétique des anticorps antistreptolysine-O dans les échantillons de sang ou de sérum, utilisant la streptolysine-O oxydée.

Publication

EP 0043608 A1 19820113 (EN)

Application

EP 81200658 A 19810612

Priority

IT 2321580 A 19800703

Abstract (en)

[origin: US4379850A] The hemolytic method for the kinetic determination of antistreptolysin O antibodies (ASO) in blood samples consists of reacting a first reagent containing a single dose of oxidized SO with the specific antibodies which may be present in the blood sample under examination, allowing the necessary time to pass for the reaction between the oxidized SO and said antibodies to take place, returning the oxidized SO to its reduced state by adding a second reagent, and measuring the rate of hemolysis. The kinetic determination of the ASO titre is obtained by comparing said rate of hemolysis with the rate of hemolysis shown graphically for samples of known ASO titre.

IPC 1-7

G01N 33/54

IPC 8 full level

G01N 33/555 (2006.01); G01N 33/557 (2006.01); A61K 39/385 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP US)

G01N 33/555 (2013.01 - EP US); G01N 33/56944 (2013.01 - EP US); Y10S 436/805 (2013.01 - EP US)

Citation (search report)

  • [X] FR 2435020 A1 19800328 - SUOVANIEMI FINNPIPETTE
  • [XD] FR 2336685 A1 19770722 - SCLAVO INST SIEROTERAPEUT [IT]
  • [A] DE 1914081 A1 19701001 - BEHRINGWERKE AG
  • [XD] CHEMICAL ABSTRACTS, vol. 89, no. 21, November 20, 1978, page 426, abstract 177775v, Columbus, Ohio, (USA) RICCI A. et al. "New hemolytic method for determination of antistreptolysin 0 in whole blood" & J. CLIN. MICROBIOL. 1978, 8(3), 263-7
  • CHEMICAL ABSTRACTS, vol. 73, no. 19, May 8, 1972, page 221, abstract 110038v, Columbus, Ohio, (USA) PALEL G. "Standardization of the thechnique for the determination of 0 antistreptolysin on plastic plates with cups" & SPITALUL 1971, 84(4), 319-26
  • [A] CHEMICAL ABSTRACTS, vol. 73, no. 1, July 6, 1970, page 174, abstract 2029x, Columbus, Ohio, (USA) BERNHEIMER A.W. et al. "Streptolysin O:activation by thiols" & INFEC. IMMUNITY 1970, 1(5), 509-10.
  • [A] CHEMICAL ABSTRACTS, vol. 78, no. 11, March 19, 1973, page 306, abstract 69995f Columbus, Ohio, (USA) REGENTOVA Yu.P. "Use of human erythrocytes during the determination of an antistreptolysin-O titer" & LAB. DELO 1972, (11),697

Designated contracting state (EPC)

AT BE CH DE FR GB LI LU NL SE

DOCDB simple family (publication)

EP 0043608 A1 19820113; EP 0043608 B1 19850911; AT E15546 T1 19850915; CA 1162846 A 19840228; CS 252455 B2 19870917; DE 3172219 D1 19851017; IT 1132167 B 19860625; IT 8023215 A0 19800703; JP S5794659 A 19820612; SU 1367838 A3 19880115; US 4379850 A 19830412

DOCDB simple family (application)

EP 81200658 A 19810612; AT 81200658 T 19810612; CA 380895 A 19810630; CS 516481 A 19810703; DE 3172219 T 19810612; IT 2321580 A 19800703; JP 9978581 A 19810629; SU 3304334 A 19810701; US 27644281 A 19810622