Global Patent Index - EP 0049861 B1

EP 0049861 B1 19850529 - THROMBINE INHIBITOR, ITS PREPARATION AND APPLICATION

Title (en)

THROMBINE INHIBITOR, ITS PREPARATION AND APPLICATION

Publication

EP 0049861 B1 19850529 (DE)

Application

EP 81108018 A 19811006

Priority

DE 3038163 A 19801009

Abstract (en)

[origin: ES8205813A1] Thrombin inhibitor comprising a glycoprotein of a molecular weight of 68,000 to 69,000 Dalton and an isoelectric point of pH 4.5, and is further characterized in that it inhibits thrombin in the presence of dextran sulfate at least twice as strongly as in the presence of heparin, differs immunologically from antithrombin III, and does not inhibit factor Xa, plasmin and trypsin.

IPC 1-7

A61K 37/64; C07K 15/14; C07K 3/18

IPC 8 full level

A61K 35/14 (2006.01); A61K 38/16 (2006.01); A61K 38/55 (2006.01); A61P 43/00 (2006.01); C07K 1/22 (2006.01); C07K 14/00 (2006.01); C07K 14/415 (2006.01); C07K 14/81 (2006.01); C12Q 1/56 (2006.01); G01N 33/52 (2006.01)

CPC (source: EP US)

A61P 43/00 (2017.12 - EP); C12Q 1/56 (2013.01 - EP US); G01N 2333/81 (2013.01 - EP US); G01N 2333/8128 (2013.01 - EP US); G01N 2333/974 (2013.01 - EP US); G01N 2400/40 (2013.01 - EP US); Y10S 530/83 (2013.01 - EP US); Y10S 530/831 (2013.01 - EP US)

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

EP 0049861 A2 19820421; EP 0049861 A3 19830727; EP 0049861 B1 19850529; AT E13489 T1 19850615; DD 201975 A5 19830824; DE 3038163 A1 19820506; DE 3170739 D1 19850704; ES 505829 A0 19820816; ES 8205813 A1 19820816; JP S5793915 A 19820611; JP S5932443 B2 19840809; SU 1271379 A3 19861115; US 4379142 A 19830405

DOCDB simple family (application)

EP 81108018 A 19811006; AT 81108018 T 19811006; DD 23391681 A 19811006; DE 3038163 A 19801009; DE 3170739 T 19811006; ES 505829 A 19810928; JP 16036881 A 19811009; SU 3450446 A 19820608; US 30966581 A 19811008