EP 0107825 B1 19880302 - 1,3,4,6,7,11B-HEXAHYDRO-7-ARYL-2H-PYRAZINO (2,1-ALPHA) ISOQUINOLINES USEFUL AS INTERMEDIATES AND PHARMACEUTICAL COMPOUNDS AND METHODS OF PREPARATION
Title (en)
1,3,4,6,7,11B-HEXAHYDRO-7-ARYL-2H-PYRAZINO (2,1-ALPHA) ISOQUINOLINES USEFUL AS INTERMEDIATES AND PHARMACEUTICAL COMPOUNDS AND METHODS OF PREPARATION
Publication
Application
Priority
US 43513282 A 19821018
Abstract (en)
[origin: EP0107825A1] Compounds of formula <CHEM> wherein R1 is hydrogen, alkyl, cycloalkyl, alkanoyl, aralkyl, aralkanoyl, aryl or aroyl and R2 and R3 are the same or independently hydrogen, halogen, hydroxy, acyloxy, nitro, amino, aminoalkyl, trifluoromethyl, alkyl, alkoxy, acyl, cyano, or alkylamino with antidepressant, antihistaminic and cholinergic activity.
IPC 1-7
IPC 8 full level
A61K 31/495 (2006.01); A61P 25/02 (2006.01); A61P 25/24 (2006.01); A61P 25/26 (2006.01); A61P 43/00 (2006.01); C07D 217/14 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP KR US)
A61P 25/02 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/26 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 217/14 (2013.01 - EP US); C07D 471/04 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0107825 A1 19840509; EP 0107825 B1 19880302; AT E32720 T1 19880315; AU 1955583 A 19840503; CA 1219874 A 19870331; DE 3375784 D1 19880407; DK 477783 A 19840419; DK 477783 D0 19831017; FI 833784 A0 19831017; FI 833784 A 19840419; IL 69586 A0 19831130; IL 69586 A 19860731; JP S5989680 A 19840523; KR 840006656 A 19841201; KR 870000622 B1 19870326; NO 833778 L 19840424; NZ 205425 A 19860509; US 4517187 A 19850514; ZA 836448 B 19840725
DOCDB simple family (application)
EP 83110044 A 19831007; AT 83110044 T 19831007; AU 1955583 A 19830926; CA 435430 A 19830826; DE 3375784 T 19831007; DK 477783 A 19831017; FI 833784 A 19831017; IL 6958683 A 19830829; JP 19002583 A 19831013; KR 830004928 A 19831018; NO 833778 A 19831017; NZ 20542583 A 19830830; US 43513282 A 19821018; ZA 836448 A 19830831