EP 0111151 A1 19840620 - Substituted nitropyrazine compounds, process for their preparation and pharmaceutical compositions containing them.
Title (en)
Substituted nitropyrazine compounds, process for their preparation and pharmaceutical compositions containing them.
Title (de)
Substituierte Nitropyrazinverbindungen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
Title (fr)
Composés de nitropyrazine substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
Publication
Application
Priority
US 44120382 A 19821112
Abstract (en)
2 or 6 substituted and 2,6-disubstituted derivatives of 3-nitropyrazine and processes for their preparation are disclosed. Said derivatives have an activity in increasing the sensitivity of tumor cells to radiation. Also disclosed are pharmaceutical compositions containing said derivatives as active ingredients.
IPC 1-7
IPC 8 full level
C07D 241/16 (2006.01); A61K 31/495 (2006.01); A61P 43/00 (2006.01); C07D 241/20 (2006.01); C07D 241/26 (2006.01); C07D 241/28 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C07D 241/20 (2013.01); C07D 241/26 (2013.01)
Citation (search report)
[A] US 3660397 A 19720502 - JONES JAMES H, et al
Designated contracting state (EPC)
CH DE FR GB IT LI NL
DOCDB simple family (publication)
EP 0111151 A1 19840620; EP 0111151 B1 19871209; DE 3374863 D1 19880121; JP S59101471 A 19840612
DOCDB simple family (application)
EP 83110974 A 19831103; DE 3374863 T 19831103; JP 21172183 A 19831112