EP 0116637 A4 19850218 - N-ALKYL-4'-HYDROXYACETANILIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE.
Title (en)
N-ALKYL-4'-HYDROXYACETANILIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE.
Title (de)
N-ALKYL-4'-HYDROXYACETANILIDE, ARZNEIMITTELZUSAMMENSETZUNGEN DIE DIESE ENTHALTEN SOWIE DEREN VERWENDUNG.
Title (fr)
N-ALKYL-4'-HYDROXYACETANILIDES, COMPOSITIONS PHARMACEUTIQUES A BASE DE CEUX-CI, AINSI QUE LEUR UTILISATION.
Publication
Application
Priority
US 41231382 A 19820827
Abstract (en)
[origin: WO8400886A1] N-alkyl-4'-hydroxyacetanilides wherein alkyl is of up to 8 carbon atoms, preferably ethyl or isopropyl, have analgesic, antipyretic, anti-inflammatory and sedative activity. Those of at least two carbon atoms lack the hepatotoxicity of acetaminophen and the N-methyl compound also has substantially less hepatotoxicity than acetaminophen. Pharmaceutical compositions comprising them are employed to ameliorate pain, reduce fever, reduce the symptoms of systemic inflammatory conditions and sedate.
IPC 1-7
IPC 8 full level
A61K 31/16 (2006.01); A61K 31/165 (2006.01)
CPC (source: EP)
A61K 31/16 (2013.01)
Citation (search report)
No further relevant documents have been disclosed.
Designated contracting state (EPC)
AT BE CH DE FR GB LI LU NL SE
DOCDB simple family (publication)
WO 8400886 A1 19840315; AU 2031183 A 19840329; DK 169584 A 19840327; DK 169584 D0 19840327; EP 0116637 A1 19840829; EP 0116637 A4 19850218; JP S59501461 A 19840816
DOCDB simple family (application)
US 8301311 W 19830826; AU 2031183 A 19830826; DK 169584 A 19840327; EP 83902969 A 19830826; JP 50303583 A 19830826