EP 0117934 A1 19840912 - Antigenic modification of polypeptides.
Title (en)
Antigenic modification of polypeptides.
Title (de)
Antigenische Modifizierung von Peptiden.
Title (fr)
Modification antigénique de polypeptides.
Publication
Application
Priority
US 47219083 A 19830304
Abstract (en)
Modified polypeptides capable of provoking the formation of antibodies in an animal may be produced by forming a linear polymer of polypeptide fragments, each having a molecular structure similar to a fragment of the protein to which antibodies are to be provoked. Such linear polymers can be made more immunogenic than the proteins to which they are related without introducing undesirable extraneous materials into the animal being treated, but have reproducable immunogenic properties. Proteins which are not endogenous or immunogenic to an animal can be chemically modified so as to make them more immunogenic. Also, modified antigens useful for fertility control can be produced by chemical modification of zona pellucida or sperm antigens. These modified polypeptides, antigens and modified antigens are desirably administered in the form of a vaccine having a vehicle comprising a mixture of mannide monooleate with Squalene and/or Squalene.
IPC 1-7
IPC 8 full level
C07K 1/113 (2006.01); A61K 38/00 (2006.01); A61K 38/24 (2006.01); A61K 39/00 (2006.01); A61K 39/385 (2006.01); C07K 1/10 (2006.01); C07K 1/107 (2006.01); C07K 1/14 (2006.01); C07K 14/00 (2006.01); C07K 14/59 (2006.01)
IPC 8 main group level
A61K (2006.01)
CPC (source: EP US)
A61K 39/00 (2013.01 - EP US); A61K 39/0006 (2013.01 - EP US); A61K 39/385 (2013.01 - EP US); C07K 1/1072 (2013.01 - EP US); C07K 1/1075 (2013.01 - EP US); C07K 1/1077 (2013.01 - EP US); C07K 14/59 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); A61K 2039/5555 (2013.01 - EP US); A61K 2039/55555 (2013.01 - EP US); A61K 2039/55566 (2013.01 - EP US); A61K 2039/6012 (2013.01 - EP US); A61K 2039/627 (2013.01 - EP US); A61K 2039/64 (2013.01 - EP US); Y10S 530/806 (2013.01 - EP US); Y10S 930/11 (2013.01 - EP US)
Citation (applicant)
- GB 1567764 A 19800521 - UNIV OHIO STATE
- US 4302386 A 19811124 - STEVENS VERNON C
- US 4320386 A 19820316 - HARRIS RAYMOND W
- W.R. JONES: "Immunological Fertility Regulation", 1982, BLACKWELL SCIENTIFIC PUBLICATIONS, pages: 160
- E.' GOLDBURG: "Reproductive Immunology", 1981, OXFORD UNIVERSITY PRESS, article "LDH-X as a sperm-specific antigen"
Citation (search report)
- [X] US 4201770 A 19800506 - STEVENS VERNON C [US]
- [XD] US 4302386 A 19811124 - STEVENS VERNON C
- [XE] US 4384995 A 19830524 - STEVENS VERNON C
- [Y] US 4234561 A 19801118 - BAHL OM P
- [Y] US 4256629 A 19810317 - BAHL OM P
- [Y] US 4313871 A 19820202 - BAHL OM P
- [Y] US 4310455 A 19820112 - BAHL OM P
- [Y] US 4268435 A 19810519 - BAHL OM P
- [Y] GB 1492445 A 19771116 - ALL INDIA INST MED [IN]
- [A] US 4253996 A 19810303 - KATZ DAVID H
- [Y] CHEMICAL ABSTRACTS, vol. 83, no. 7, 18th August 1975, page 331, no. 56613h, Columbus, Ohio, USA
Designated contracting state (EPC)
AT BE CH DE FR IT LI LU NL SE
DOCDB simple family (publication)
US 4526716 A 19850702; AU 1704083 A 19840928; AU 570004 B2 19880303; AU 588448 B2 19890914; AU 594453 B2 19900308; AU 7149087 A 19870806; AU 7149587 A 19870910; DK 167222 B1 19930920; DK 521584 A 19841102; DK 521584 D0 19841102; EP 0117934 A1 19840912; EP 0117934 B1 19880720; EP 0210628 A2 19870204; EP 0210628 A3 19890208; EP 0213391 A2 19870311; EP 0213391 A3 19890201; FI 80603 B 19900330; FI 80603 C 19900710; FI 844288 A0 19841101; FI 844288 L 19841101; GB 2146646 A 19850424; GB 2178041 A 19870204; GB 2178041 B 19880106; GB 2178042 A 19870204; GB 2178042 B 19880106; GB 8425710 D0 19841205; GB 8619232 D0 19860917; GB 8619233 D0 19860917; GR 79126 B 19841002; IL 68749 A 19880731; JP H0557999 B2 19930825; JP S60500814 A 19850530; WO 8403443 A1 19840913
DOCDB simple family (application)
US 47219083 A 19830304; AU 1704083 A 19830518; AU 7149087 A 19870413; AU 7149587 A 19870413; DK 521584 A 19841102; EP 83302888 A 19830520; EP 86110377 A 19830520; EP 86110378 A 19830520; FI 844288 A 19841101; GB 8425710 A 19830518; GB 8619232 A 19860806; GB 8619233 A 19860806; GR 830171441 A 19830524; IL 6874983 A 19830520; JP 50204683 A 19830518; US 8300777 W 19830518