EP 0124058 A1 19841107 - Preparation of a pharmaceutically active pyridazine derivative.
Title (en)
Preparation of a pharmaceutically active pyridazine derivative.
Title (de)
Herstellung von pharmazeutisch wirksamen Pyridazin-Derivat.
Title (fr)
Préparation de dérivé de pyridazine pharmacologiquement actif.
Publication
Application
Priority
IT 2081383 A 19830428
Abstract (en)
[origin: ES8505968A1] Preparation of ethyl {6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl} hydrazino carboxylate is disclosed from 3-chloro-6-hydrazinopyridazine in protected form, which is oxidized to yield the corresponding azo derivative, which is treated with ethyl-(2-hydroxypropyl)amine in the presence of strong bases, the corresponding amino derivative being subjected to reduction and deprotection, and finally acylated to yield ethyl {6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl} hydrazinocarboxylate.
IPC 1-7
IPC 8 full level
C07D 237/20 (2006.01)
CPC (source: EP KR US)
C07D 237/20 (2013.01 - EP KR US)
Citation (search report)
[A] GB 1470747 A 19770421 - ISF SPA
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI NL SE
DOCDB simple family (publication)
EP 0124058 A1 19841107; AU 2747184 A 19841101; AU 561504 B2 19870507; CA 1212948 A 19861021; DK 211384 A 19841029; DK 211384 D0 19840427; ES 531544 A0 19850616; ES 8505968 A1 19850616; FI 841637 A0 19840426; FI 841637 A 19841029; GR 81992 B 19841212; IL 71588 A0 19840731; IL 71588 A 19870916; IT 1212734 B 19891130; IT 8320813 A0 19830428; JP H0513948 B2 19930223; JP S59206362 A 19841122; JP S6153347 B2 19861117; JP S63290866 A 19881128; KR 840008331 A 19841214; KR 910007241 B1 19910924; NO 841710 L 19841029; PH 19157 A 19860115; PT 78440 A 19840501; PT 78440 B 19860527; US 4575552 A 19860311; US 4632982 A 19861230; YU 44988 B 19910630; YU 76584 A 19861031; ZA 842852 B 19861029
DOCDB simple family (application)
EP 84104560 A 19840422; AU 2747184 A 19840427; CA 452026 A 19840413; DK 211384 A 19840427; ES 531544 A 19840412; FI 841637 A 19840426; GR 840174538 A 19840427; IL 7158884 A 19840419; IT 2081383 A 19830428; JP 23638487 A 19870922; JP 8208684 A 19840425; KR 840002227 A 19840426; NO 841710 A 19840427; PH 30616 A 19840427; PT 7844084 A 19840417; US 60040784 A 19840416; US 83143486 A 19860220; YU 76584 A 19840427; ZA 842852 A 19840416