EP 0146563 A4 19881107 - IMMUNOASSAY FOR HUMAN CHORIONIC GONADOTROPIN.
Title (en)
IMMUNOASSAY FOR HUMAN CHORIONIC GONADOTROPIN.
Title (de)
IMMUNOASSAY FÜR MENSCHLICHES CHORIONISCHES GONADOTROPIN.
Title (fr)
ANALYSE IMMUNOLOGIQUE DE LA GONADOTROPINE CHORIONIQUE HUMAINE.
Publication
Application
Priority
US 49221083 A 19830506
Abstract (en)
[origin: WO8404598A1] An immunoassay for detecting and measuring hCG in a sample includes an antibody directed to the carboxy terminal portion of the beta subunit of hCG and a monoclonal antibody directed to a determinant on hCG at a locus sufficiently remote from the carboxy terminal portion of the beta subunit of hCG that both antibodies can simultaneously bind to hCG, wherein at least one of the antibodies is detectable when both are bound to hCG. In a presently preferred embodiment, an immunoassay for hCG or hCG beta in urine includes a purified, labeled or detectable serum-derived antibody directed to the carboxy-terminal portion of the beta subunit of hCG and a matrix-bound monoclonal antibody directed to a locus on the beta subunit sufficiently remote from the carboxy-terminal portion that both antibodies can simultaneously bind to hCG or hCG beta .
IPC 1-7
IPC 8 full level
G01N 33/50 (2006.01); A61K 39/00 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01); C07K 14/415 (2006.01); C07K 14/575 (2006.01); C07K 16/00 (2006.01); C07K 19/00 (2006.01); C12N 15/00 (2006.01); C12N 15/02 (2006.01); C12Q 1/00 (2006.01); C12Q 1/70 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); G01N 33/577 (2006.01); G01N 33/76 (2006.01)
CPC (source: EP)
G01N 33/57476 (2013.01); G01N 33/76 (2013.01)
Citation (search report)
- [A] EP 0062892 A1 19821020 - HOECHST CO AMERICAN [US]
- See references of WO 8404598A1
Designated contracting state (EPC)
AT BE CH DE FR GB LI LU NL SE
DOCDB simple family (publication)
WO 8404598 A1 19841122; CA 1229549 A 19871124; EP 0146563 A1 19850703; EP 0146563 A4 19881107; JP S60501271 A 19850808
DOCDB simple family (application)
US 8400572 W 19840413; CA 452265 A 19840418; EP 84901866 A 19840413; JP 50209384 A 19840413