EP 0147437 A4 19870305 - DRY DIRECT COMPRESSION COMPOSITIONS FOR CONTROLLED RELEASE DOSAGE FORMS.
Title (en)
DRY DIRECT COMPRESSION COMPOSITIONS FOR CONTROLLED RELEASE DOSAGE FORMS.
Title (de)
TROCKENE ZUSAMMENSETZUNGEN MIT DIREKTEM ZUSAMMENDRUCK FÜR DOSIERUNGSFORMEN MIT KONTROLLIERBARER VERABREICHUNG.
Title (fr)
COMPOSITIONS SECHES A COMPRESSION DIRECTE POUR FORMES DE DOSAGE A LIBERATION CONTROLEE.
Publication
Application
Priority
- US 49922183 A 19830531
- US 60047284 A 19840416
Abstract (en)
[origin: WO8404674A1] The selection of: a hydrophobic carbohydrate polymer, e.g. ethyl cellulose; and, generally at least one digestive-difficulty soluble component, i.e., a wax, e.g. carnauba wax, fatty acid material or neutral lipid provides upon dry direct compression a controlled and continuous release matrix for tablets or implants of biologically active agents. Preferred for producing dry direct compressed products is the combination of: a hydrophobic cellulose derivative; a wax, and, a fatty acid material and/or a neutral lipid since it provides upon dry direct compression a controlled and continuous release tablet or implant of improved structurally integrity against externally imposed forces.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/22 (2006.01); A61K 9/26 (2006.01)
CPC (source: EP)
A61K 9/2013 (2013.01); A61K 9/2054 (2013.01)
Citation (search report)
- [X] DE 2050701 A1 19710506
- [A] US 3108046 A 19631022 - HARBIT KEITH B
- See references of WO 8404674A1
Designated contracting state (EPC)
AT BE CH DE FR GB LI LU NL SE
DOCDB simple family (publication)
WO 8404674 A1 19841206; AU 2967684 A 19841218; AU 3475189 A 19890907; AU 581177 B2 19890216; BR 8406921 A 19850604; EP 0147437 A1 19850710; EP 0147437 A4 19870305; JP H0759502 B2 19950628; JP S60501459 A 19850905
DOCDB simple family (application)
US 8400807 W 19840529; AU 2967684 A 19840529; AU 3475189 A 19890515; BR 8406921 A 19840529; EP 84902301 A 19840529; JP 50229284 A 19840529