Global Patent Index - EP 0149241 A3

EP 0149241 A3 19870527 - DNA BASE SEQUENCE CONTAINING REGIONS INVOLVED IN THE PRODUCTION AND SECRETION OF A PROTEIN, RECOMBINANT DNA INCLUDING THE WHOLE OR A PART OF THE DNA BASE SEQUENCE, AND METHOD OF PRODUCING PROTEINS BY USE OF THE RECOMBINANT DNA

Title (en)

DNA BASE SEQUENCE CONTAINING REGIONS INVOLVED IN THE PRODUCTION AND SECRETION OF A PROTEIN, RECOMBINANT DNA INCLUDING THE WHOLE OR A PART OF THE DNA BASE SEQUENCE, AND METHOD OF PRODUCING PROTEINS BY USE OF THE RECOMBINANT DNA

Publication

EP 0149241 A3 19870527 (EN)

Application

EP 84116373 A 19841227

Priority

  • JP 6515684 A 19840403
  • JP 17515884 A 19840824
  • JP 24506583 A 19831228

Abstract (en)

[origin: EP0149241A2] This invention relates to a DNA base sequence containing regions involved in the production and secretion of a protein, a recombinant DNA including the whole or a part of said DNA base sequence, and a method of producing proteins which comprises introducing said recombinant DNA into a microorganism, culturing this microorganism and thereby causing the protein to be extracellularly secreted in large amounts, and then recovering the protein.

IPC 1-7

C12N 15/00; C12N 9/54; C12P 21/02; C07H 21/04

IPC 8 full level

C12N 9/54 (2006.01); C12N 15/75 (2006.01)

CPC (source: EP US)

C12N 9/54 (2013.01 - EP US); C12N 15/75 (2013.01 - EP US); C07K 2319/02 (2013.01 - EP US); C07K 2319/036 (2013.01 - EP US)

Citation (search report)

  • [E] EP 0151760 A1 19850821 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
  • [E] EP 0130756 B1 19910206
  • [E] EP 0133756 A2 19850306 - GENEX CORP [US]
  • [E] EP 0134048 A1 19850313 - GIST BROCADES NV [NL]
  • [E] EP 0181634 A2 19860521 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
  • [E] EP 0179025 A1 19860423 - ENIRICERCHE SPA [IT]
  • [X] JOURNAL OF BACTERIOLOGY, vol. 154, no. 2, May 1983, pages 831-837, American Society for Microbiology; MIKIO FUJII et al.: "Molecular cloning of a thermostable neutral protease gene from Bacillus stearothermophilus in a vector plasmid and its expression in Bacillus stearothermophilus and Bacillus subtilis"
  • [X] PATENTS ABSTRACTS OF JAPAN, vol. 7, no. 285 (C-201)[1430], 20th December 1983; & JP-A-58 162 291 (SHINGIJIYUTSU KAIHATSU JIGIYOUDAN) 26-09-1983
  • [Y] CHEMICAL ABSTRACTS, vol. 84, no. 5, 2nd February 1976, page 175, abstract no. 27437u, Columbus, Ohio, US; P.L. LEVY et al.: "Evidence of homologous relation between thermolysin and neutral protease A of Bacillus subtilis", & PROC. NATL. ACAD. SCI. U.S.A. 1975, 72(11), 4341-5
  • [XP] PATENTS ABSTRACTS OF JAPAN, vol. 8, no. 156 (C-234)[1593], 19th July 1984; & JP-A-59 059 190 (KOGYO GIJUTSUIN (JAPAN)) 04-04-1984
  • [XP] JOURNAL OF BACTERIOLOGY, vol. 159, no. 3, September 1984, pages 811-819, American Society for Microbiology; N. VASANTHA et al.: "Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein"
  • [XP] CHEMICAL ABSTRACTS, vol. 103, no. 11, 16th September 1985, page 158, abstract no. 82709v, Columbus, Ohio, US; M. HONJO et al.: "Cloning and expression of the gene for neutral protease of Bacillus amyloliquefaciens in Bacillus subtilis", & J. BIOTECHNOL. 1984, 1(5-6), 265-77
  • [E] PATENTS ABSTRACTS OF JAPAN, vol. 10, no. 71 (C-334)[2128], 20th March 1986; & JP-A-60 210 986 (KOGYO GIJUTSUIN (JAPAN)) 23-10-1985
  • [E] PATENTS ABSTRACTS OF JAPAN, vol. 9, no. 301 (C-316)[2024], 28th November 1985; & JP-A-60 141 291 (KOGYO GIJUTSUIN (JAPAN)) 26-07-1985
  • [E] PATENTS ABSTRACTS OF JAPAN, vol. 10, no. 63 (C-332)[2120], 13th March 1986; & JP-A-60 203 194 (TAKEDA YAKUHIN KOGYO K.K.) 14.10.1985

Designated contracting state (EPC)

CH DE FR LI NL

DOCDB simple family (publication)

EP 0149241 A2 19850724; EP 0149241 A3 19870527; EP 0149241 B1 19910327; DE 3484346 D1 19910502; US 5612192 A 19970318

DOCDB simple family (application)

EP 84116373 A 19841227; DE 3484346 T 19841227; US 35986394 A 19941220