Title (en)

ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE.

Title (de)

ANTIMIKROBIELLE ZUSAMMENSETZUNGEN ENTHALTEND 1-ÄTHYL-6-FLUOR-1,4-DIHYDROXY-4-OXO-7(1-PIPERAZINYL)-3-CHINOLIN KARBONSÄURE ODER DEREN METALLSALZE UND SILBERSULFADIAZIN.

Title (fr)

COMPOSITIONS ANTIMICROBIENNES CONTENANT DE L'ACIDE CARBOXYLIQUE DE 1-ETHYL-6-FLUORO-1,4-DIHYDRO-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE OU SES SELS METALLIQUES ET DE LA SULFADIAZINE D'ARGENT.

Publication

EP 0154622 A4 19870316 (EN)

Application

EP 83903134 A 19830912

Priority

US 8301376 W 19830912

Abstract (en)

[origin: WO8501208A1] Compositions which include 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid or its metal salts, e.g., silver, zinc, cobalt or cerium salts, and silver sulfadiazine are effective in the treatment of burns. Of special interest are compositions containing silver sulfadiazine and the silver salt of the above-identified quinoline carboxylic acid, wherein even though each compound is present in a concentration which would be ineffective if either compound were present alone, the resulting compositions are effective. The compositions of this invention may be applied to the affected surface of a burn victim either directly or in combination with a physiologically acceptable carrier, such as a water-dispersible, hydrophilic carrier.

IPC 1-7

A61K 31/495; A61K 31/625

IPC 8 full level

A61K 31/635 (2006.01)

CPC (source: EP)

A61K 31/635 (2013.01)

Citation (search report)

• No relevant documents have been disclosed.
• See references of WO 8501208A1

Designated contracting state (EPC)

BE DE FR GB NL

DOCDB simple family (publication)

WO 8501208 A1 19850328; EP 0154622 A1 19850918; EP 0154622 A4 19870316; JP S61500067 A 19860116

DOCDB simple family (application)

US 8301376 W 19830912; EP 83903134 A 19830912; JP 50320283 A 19830912