EP 0161468 A2 19851121 - Process for the solid phase synthesis of peptides which contain sulfated tyrosine.
Title (en)
Process for the solid phase synthesis of peptides which contain sulfated tyrosine.
Title (de)
Festphasen-Peptidsynthese welche sulfatiertes Tyrosin enthält.
Title (fr)
Procédé de synthèse de peptide en phase solide contenant de la tyrosine sulfatée.
Publication
Application
Priority
- US 60748584 A 19840507
- US 70797585 A 19850304
Abstract (en)
Peptides and Peptide amides such as chlolecystokinin (CCK-8) are synthesized in improved yields and purity by a solid phase process. The requisite protected peptide is elaborated and sulfated on a solid support, deprotected, and cleaved from the solid support to give the total synthesis of CCK-8 on a solid support. Thereafter, the peptide is purified in a single step by ion exchange chromatography to provide analytically pure CCK-8.
IPC 1-7
IPC 8 full level
C07K 1/00 (2006.01); C07K 1/04 (2006.01); C07K 1/06 (2006.01); C07K 1/113 (2006.01); C07K 7/06 (2006.01); C07K 14/575 (2006.01); C07K 14/595 (2006.01)
CPC (source: EP)
C07K 1/006 (2013.01); C07K 1/04 (2013.01); C07K 1/042 (2013.01); C07K 14/595 (2013.01)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0161468 A2 19851121; EP 0161468 A3 19881026; JP S6122098 A 19860130
DOCDB simple family (application)
EP 85104155 A 19850404; JP 9396185 A 19850502