Global Patent Index - EP 0167443 A3

EP 0167443 A3 19870603 - COCCIDIOSIS VACCINE

Title (en)

COCCIDIOSIS VACCINE

Publication

EP 0167443 A3 19870603 (EN)

Application

EP 85401246 A 19850621

Priority

US 62588284 A 19840629

Abstract (en)

[origin: EP0167443A2] Sporozoites of coccidia fail to develop in chickens which are immune and many are blocked from penetrating host cells. Although previous attempts to immunize chickens with non-viable coccidial antigens have been unsuccessful it has been discovered that extracts from sporozoites or sporulated oocysts of E. tenella induce high levels of protective immunity. These extracts contain at least 15 polypeptides many of which are associated with the surface of the sporozoite and induce good immune responses. Antibody to these polypeptides blocks sporozoite-host cell penetration in vitro and neutralizes sporozoites in vivo. One or more of these polypeptides may be used as an antigen to protect against coccidiosis.

IPC 1-7

A61K 39/012

IPC 8 full level

A61K 39/012 (2006.01); C07K 14/455 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP US)

A61K 39/012 (2013.01 - EP US); C07K 14/455 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US)

Citation (search report)

  • [XP] EP 0135073 A2 19850327 - AMERICAN CYANAMID CO [US]
  • [XP] EP 0135712 A2 19850403 - AMERICAN CYANAMID CO [US]
  • [E] EP 0164176 A2 19851211 - SOLVAY [BE]
  • [E] WO 8600528 A1 19860130 - GENEX CORP [US]
  • [X] J. CELL BIOCHEM., Suppl. 1983, vol. O, no. 7, Part A, 12th annual Symp. on Molecular Biology of Host-Parasite interactions, January 30 - February 4, 1983, page 25, ref.no. 0059; M.H. WISHER: "Sporozoite antigens of coccidia."
  • [A] PROTOZOOL, vol. 30, no. 3, August 1983, pages 548-554; soc. of Protozoologists, (US) C.A. SPEER et al.: "Ultrastructural localization of monoclonal IgG antibodies for antigenic sites of Eimeria tenella oocysts, sporocysts, and sporozoites."
  • [AO] SYMPOSIUM OF THE BRITISH SOCIETY FOR PARASITOLOGY, vol. 18, 1980, pages 57-74; M.E. ROSE et al.: "Vaccination against coccidiosis in chickens."
  • [A] JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 251, no. 2, January 25, 1976, pages 302-307; (US) R.L. STOTISH et al.: "Studies of a glycoprotein in the oocysts of Eimeria tenella."

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL

DOCDB simple family (publication)

EP 0167443 A2 19860108; EP 0167443 A3 19870603; AU 4428085 A 19860102; AU 569455 B2 19880128; CA 1270758 A 19900626; EG 17184 A 19900630; ES 544638 A0 19861016; ES 8700057 A1 19861016; JP S6118724 A 19860127; NZ 212474 A 19880728; US 4639372 A 19870127; ZA 854900 B 19860226

DOCDB simple family (application)

EP 85401246 A 19850621; AU 4428085 A 19850628; CA 484494 A 19850619; EG 38985 A 19850627; ES 544638 A 19850627; JP 14067385 A 19850628; NZ 21247485 A 19850619; US 62588284 A 19840629; ZA 854900 A 19850628