EP 0177915 A3 19870805 - NOVEL DNA, PRODUCTION AND USE THEREOF
Title (en)
NOVEL DNA, PRODUCTION AND USE THEREOF
Publication
Application
Priority
- JP 17697685 A 19850813
- JP 21050284 A 19841009
Abstract (en)
[origin: EP0177915A2] The present invention presents a DNA containing a synthetic gene for expression of human epidermal cell growth factor of the DNA sequence:The adoption of the DNA of the present invention improves the stability of mRNA, the translation efficiency and the influence of the high-dimensional structure which is determined by the mRNA sequence, and made it possible to produce hEGF efficiently.
IPC 1-7
IPC 8 full level
C07K 14/485 (2006.01); C12N 15/70 (2006.01)
CPC (source: EP US)
C07K 14/485 (2013.01 - EP US); C12N 15/70 (2013.01 - EP US)
Citation (search report)
- [A] EP 0075444 B1 19921223
- [A] WO 8304030 A1 19831124 - APPLIED MOLECULAR GENETICS INC [US]
- [A] PROC. NATL. ACAD. SCI. USA, vol. 80, December 1983, pages 7461-7465; M.S. URDEA et al.: "Chemical synthesis of a gene for human epidermal growth factor urogastrone and its expression in yeast"
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0177915 A2 19860416; EP 0177915 A3 19870805; EP 0177915 B1 19910109; CA 1263619 A 19891205; DE 3581255 D1 19910214; US 4849350 A 19890718
DOCDB simple family (application)
EP 85112653 A 19851005; CA 492430 A 19850908; DE 3581255 T 19851005; US 78484485 A 19851004