EP 0196024 B1 19901122 - SUBSTITUTED 1,8-NAPHTHYRIDINONES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (en)
SUBSTITUTED 1,8-NAPHTHYRIDINONES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Publication
Application
Priority
- US 71600385 A 19850325
- US 83635786 A 19860310
Abstract (en)
[origin: EP0196024A1] Substituted 1,8-naphthyridinones of formulae V, VI or VII <CHEM> wherein n is 1 or 2; R<1> and R<2> may be combined to form a bond, or R<1> is hydrogen and R<2> is OR, halogen or NR<3>R<4>; R is hydrogen, carboxylic acyl or carbamyl; R<3> and R<4> are independently hydrogen or alkyl having from 1 to 6 carbon atoms, or R<3> and R<4> may be combined with the nitrogen to which they are attached to form a pyrrolidino, piperidino, morpholino or piperazino ring; R<5> is hydrogen or carboxylic acyl; and Y is CH or N. The compounds possess anti-allergic, anti-inflammatory, cytoprotective activity and an immuno-suppressing effect.
IPC 1-7
IPC 8 full level
C07D 491/00 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01); A61K 31/495 (2006.01); A61K 31/535 (2006.01); C07D 491/14 (2006.01); C07D 491/147 (2006.01)
CPC (source: EP KR)
A61K 31/44 (2013.01 - EP); A61K 31/445 (2013.01 - EP); A61K 31/495 (2013.01 - EP); A61K 31/535 (2013.01 - EP); C07D 491/00 (2013.01 - KR); C07D 491/14 (2013.01 - EP); C07D 491/147 (2013.01 - KR)
Citation (examination)
The Merck Manual (1982) 14th edition, p. 265
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0196024 A1 19861001; EP 0196024 B1 19901122; AU 5502786 A 19861002; AU 579718 B2 19881208; DE 3675671 D1 19910103; DK 127086 A 19860926; DK 127086 D0 19860319; FI 84828 B 19911015; FI 84828 C 19920127; FI 861194 A0 19860321; FI 861194 A 19860926; GR 860757 B 19860728; HU 196074 B 19880928; HU T41797 A 19870528; IL 78230 A0 19860731; KR 860007263 A 19861010; KR 900004829 B1 19900707; NO 164657 B 19900723; NO 164657 C 19901031; NO 861178 L 19860926; NZ 215562 A 19881129; OA 08271 A 19871030; PT 82257 A 19860401; PT 82257 B 19880729
DOCDB simple family (application)
EP 86103874 A 19860321; AU 5502786 A 19860321; DE 3675671 T 19860321; DK 127086 A 19860319; FI 861194 A 19860321; GR 860100757 A 19860321; HU 123086 A 19860325; IL 7823086 A 19860321; KR 860002206 A 19860325; NO 861178 A 19860324; NZ 21556286 A 19860321; OA 58819 A 19860324; PT 8225786 A 19860324