EP 0208764 A4 19871008 - METHOD FOR PRESERVING LIPOSOMES.
Title (en)
METHOD FOR PRESERVING LIPOSOMES.
Title (de)
KONSERVIERUNGSVERFAHREN FÜR LIPOSOME.
Title (fr)
PROCEDE DE CONSERVATION DE LIPOSOMES.
Publication
Application
Priority
US 69067985 A 19850111
Abstract (en)
[origin: WO8603938A1] A novel method is provided for preserving liposomes containing biologically active molecules, such that when rehydrated, liposome structures retain substantially all material originally encapsulated. A preserving agent having at least two monosaccharide units is used either internally or externally or both. In a preferred embodiment, trehalose is used as a preserving agent, both inside the liposomes as an encapsulate material and externally, in solution, during freeze-drying. The invention also includes a lyophilized composition prepared by the disclosed method.
IPC 1-7
A01N 25/00; A61K 39/00; A01N 63/02; A61J 5/00; C12N 11/02; A61K 37/00
IPC 8 full level
A61K 49/00 (2006.01); A01N 25/00 (2006.01); A01N 63/02 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 49/22 (2006.01)
CPC (source: EP)
A61K 9/127 (2013.01); A61K 49/227 (2013.01)
Citation (search report)
- [X] GB 2002319 A 19790221 - BATTELLE MEMORIAL INSTITUTE
- [E] WO 8601103 A1 19860227 - LIPOSOME CO INC [US]
- [XP] WO 8504326 A1 19851010 - BIOCOMPATIBLES LTD [GB]
- See references of WO 8603938A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8603938 A1 19860717; AU 5318386 A 19860729; AU 587600 B2 19890824; CA 1275248 C 19901016; DK 175799 B1 20050228; DK 428386 A 19861111; DK 428386 D0 19860908; EP 0208764 A1 19870121; EP 0208764 A4 19871008; JP S62501631 A 19870702
DOCDB simple family (application)
US 8600016 W 19860108; AU 5318386 A 19860108; CA 499252 A 19860109; DK 428386 A 19860908; EP 86900891 A 19860108; JP 50064286 A 19860108