EP 0209543 A4 19890711 - PEPTIDE FRAGMENTS OF HUMAN APOLIPOPROTEIN, TYPE-SPECIFIC ANTIBODIES AND METHODS OF USE.
Title (en)
PEPTIDE FRAGMENTS OF HUMAN APOLIPOPROTEIN, TYPE-SPECIFIC ANTIBODIES AND METHODS OF USE.
Title (de)
PEPTIDFRAGMENTE MENSCHLICHER APOLIPOPROTEINE, TYPSPEZIFISCHE ANTIKÖRPER UND VERWENDUNGSVERFAHREN.
Title (fr)
FRAGMENTS DE PEPTIDES D'APOLIPOPROTEINES HUMAINES, ANTICORPS SPECIFIQUES DU TYPE ET PROCEDES D'UTILISATION.
Publication
Application
Priority
US 68804084 A 19841231
Abstract (en)
[origin: WO8604144A1] Peptide fragments of certain apolipoproteins have been found to be both immunogenic and capable of eliciting antibodies with highly apolipoprotein-specific immunoreactivity. These antibodies, in labeled and unlabeled form, as well as the labeled synthetic peptide fragments, are useful in the production of immunodiagnostic procedures and kits for quantitating type-specific apolipoproteins. Both competitive assays and immunometric assays are disclosed.
IPC 1-7
IPC 8 full level
G01N 33/532 (2006.01); A61K 39/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 14/775 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01)
CPC (source: EP)
C07K 14/775 (2013.01); C07K 16/18 (2013.01)
Citation (search report)
- EP 0044170 A1 19820120 - BEECHAM GROUP PLC [GB]
- CHEMICAL ABSTRACTS, Vol. 94, 1981, page 108, Ref. No. 11810f; Columbus, Ohio, US, J.P. KUPFERBERG et al.: "Synthetic apolipoprotein model peptides: Structural determinants of peptide-phospholipid interactions", & Pept. Struct. Biol. Funct., Proc. Am. Pept. Symp. 6th, 1979, 519-22, Abstract.
- CHEMICAL ABSTRACTS, Vol. 94, 1981, page 129, Ref. No. 1241g; Columbus, Ohio, US, J.T. SPARROW et al.: "Lipid binding by apolipoprotein A-I: Synthetic studies", & Pept. Struct. Biol. Funct., Proc. Am. Pept. Symp. 6th, 1979, 523-6, Abstract.
- CHEMICAL ABSTRACTS, Vol. 99, 1983, page 258, Ref. No. 154205b; Columbus, Ohio, US, P. VAINIO et al.: "Esterase type of activity possessed by human plasma apolipoprotein C-II and its synthetic fragments", & Chem. Phys. Lipids 1983, 33(1), 21-32, Abstract.
- Biochemistry, Vol. 16, No. 19, 1977, pages 4150-4156; S.J.T. MAO et al.: "Mechanism of lipid-protein interaction in the plasma lipoproteins: Lipid-binding properties of synthetic fragments of apolipoprotein A-II", Abstract.
- Biochemical & Biophysical Research Communications, Vol. 80, 1978, pages 623-630; H.B. BREWER et al.: "The amino acid sequence of human APOA-I, an apolipoprotein isolated from high density lipoproteins", whole article.
- Journal of Biological Chemistry, Vol. 257, No. 8, April 25, 1982, pages 4171-4178; US, S.C. RALL Jr. et al.: "Human apolipoprotein E. The complete amino acid sequence", page 4171, column 1.
- Annual Review Biochemistry, Vol. 44, 1975, pages 183-207; J.D. MORRISETT et al.: "Lipoproteins: Structure and function", whole article.
- Febs Letters, Vol. 170, No. 1, May 1984, pages 105-108; Elsevier Sc. Publ. B.V., R.C. LEBOEUF et al.: "Human apolipoprotein B: Partial amino acid sequence", Abstract.
- See references of WO 8604144A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8604144 A1 19860717; EP 0209543 A1 19870128; EP 0209543 A4 19890711; JP S62501770 A 19870716
DOCDB simple family (application)
US 8502569 W 19851226; EP 86900570 A 19851226; JP 50054386 A 19851226