EP 0218209 A3 19880831 - YEAST PROMOTER AND PROCESS FOR PREPARING HETEROLOGOUS PROTEIN
Title (en)
YEAST PROMOTER AND PROCESS FOR PREPARING HETEROLOGOUS PROTEIN
Publication
Application
Priority
- JP 2119886 A 19860204
- JP 21919185 A 19851003
Abstract (en)
[origin: EP0218209A2] A DNA sequence of the yeast glyceraldehyde -3-phosphate dehydrogenase (GAP-DH) promoter and a process for preparing a heterologous protein utilizing said DNA sequence as a promoter are disclosed, said GAP-DH promoter comprising a region upstream of an initiator codon of the GAP-DH protein up to -164 bp as a minimum unit. Since the GAP-DH promoter is small in size, a physiologically active substance can be expressed in yeasts effectively and recombination of DNA can be simplified.
IPC 1-7
IPC 8 full level
C07K 14/02 (2006.01); C12N 15/81 (2006.01)
CPC (source: EP US)
C07K 14/005 (2013.01 - EP US); C12N 15/81 (2013.01 - EP US); C12N 2730/10122 (2013.01 - EP US)
Citation (search report)
- [XP] EP 0164556 A2 19851218 - CHIRON CORP [US]
- [AD] EP 0120551 A2 19841003 - CHIRON CORP [US]
- [A] GENE, vol. 32, no. 3, part 2, December 1984, pages 263-274, Elsevier Science Publishers, Amsterdam, NL; G.A. BITTER et al.: "Expression of heterologous genes in Saccharomyces cerevisiae from vectors utilizing the glyceraldehyde-3-phosphate dehydrogenase gene promoter"
- [A] CELL, vol. 37, February 1984, pages 629-633, Cambridge, Massachusetts, US; L. EDENS et al.: "Synthesis and processing of the plant protein thaumatin in yeast"
Designated contracting state (EPC)
BE CH DE ES FR GB LI NL SE
DOCDB simple family (publication)
EP 0218209 A2 19870415; EP 0218209 A3 19880831; EP 0218209 B1 19920205; DE 3683821 D1 19920319; ES 2028779 T3 19920716; US 5021339 A 19910604
DOCDB simple family (application)
EP 86113675 A 19861003; DE 3683821 T 19861003; ES 86113675 T 19861003; US 39734789 A 19890824