EP 0221463 A2 19870513 - Quinoline derivatives and processes for preparation thereof.

Title (en)

Quinoline derivatives and processes for preparation thereof.

Title (de)

Chinolinderivate und Verfahren zu deren Herstellung.

Title (fr)

Dérivés de la quinoléine etleurs procédés de préparation.

Publication

EP 0221463 A2 19870513 (EN)

Application

EP 86114748 A 19861023

Priority

JP 3262786 A 19860217
JP 24225785 A 19851029
JP 28532385 A 19851217

Abstract (en)

The present invention relates to a quinoline derivative of the formulawherein Z is an amino group or a halogen atom, R, is a hydrogen atom or a methyl or ethyl group, R2 is a hydrogen atom or a methyl or fluoromethyl group, R3 and R4 are the same or different and each represents a hydrogen atom or a methyl group, and n is 1 or 2; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.

IPC 1-7

A61K 31/47; A61K 31/53; A61K 31/55; C07D 215/56; C07D 401/04

IPC 8 full level

C07D 401/04 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/495 (2006.01); A61K 31/535 (2006.01); A61K 31/55 (2006.01); A61P 31/04 (2006.01); C07D 215/00 (2006.01); C07D 215/22 (2006.01); C07D 215/56 (2006.01); C07D 241/04 (2006.01); C07D 243/08 (2006.01); C07D 401/02 (2006.01); C07D 413/04 (2006.01); C07D 487/08 (2006.01)

IPC 8 main group level

A61K (2006.01)

CPC (source: EP KR US)

A61P 31/04 (2018.01 - EP); C07D 215/56 (2013.01 - EP US); C07D 401/04 (2013.01 - EP KR US)

Citation (applicant)

JP S58174367 A 19831013 - TANABE SEIYAKU CO
ZA 852369 B 19851224 - ABBOTT LAB
EP 0172651 A1 19860226 - WARNER LAMBERT CO [US]
EP 0113093 A1 19840711 - BAYER AG [DE]
EP 0160578 A1 19851106 - DAIICHI SEIYAKU CO [JP]

Designated contracting state (EPC)

AT BE CH DE ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

EP 0221463 A2 19870513; EP 0221463 A3 19871202; EP 0221463 B1 19910814; AR 242031 A1 19930226; AR 243178 A1 19930730; AR 243520 A1 19930831; AT E109472 T1 19940815; AT E66210 T1 19910815; AU 594983 B2 19900322; AU 6427786 A 19870430; CA 1340402 C 19990223; CN 1009930 B 19901010; CN 86107491 A 19870429; DE 10075028 I1 20001214; DE 10075028 I2 20040129; DE 3650018 D1 19940908; DE 3650018 T2 19950105; DE 3680859 D1 19910919; DK 170593 B1 19951106; DK 170774 B1 19960115; DK 25992 A 19920228; DK 25992 D0 19920228; DK 514586 A 19870430; DK 514586 D0 19861028; EP 0375658 A1 19900627; EP 0375658 B1 19940803; ES 2029786 T3 19921001; ES 2057197 T3 19941016; FI 864299 A0 19861023; FI 864299 A 19870430; FI 87457 B 19920930; FI 87457 C 19930111; GE P19960467 B 19960527; GR 3002475 T3 19921230; HU 200452 B 19900628; HU T43839 A 19871228; IL 80404 A0 19870130; IL 80404 A 19900610; JP H0541633 B2 19930624; JP H0543551 A 19930223; JP H0714918 B2 19950222; JP S62277362 A 19871202; KR 870004019 A 19870506; KR 910006806 B1 19910902; LU 88596 I2 19950710; LU 90621 I2 20001009; MY 100574 A 19901215; NL 300014 I1 20001002; NL 300014 I2 20010201; NL 970020 I1 19970801; NL 970020 I2 19980105; NO 170726 B 19920817; NO 170726 C 19921125; NO 864247 D0 19861023; NO 864247 L 19870430; NZ 218089 A 19890329; PH 22862 A 19890119; PT 83643 A 19861101; PT 83643 B 19881014; SU 1598873 A3 19901007; SU 1635898 A3 19910315; US 4795751 A 19890103; YU 137191 A 19940120; YU 137291 A 19940120; YU 183586 A 19880430; YU 46414 B 19931020

DOCDB simple family (application)

EP 86114748 A 19861023; AR 30574286 A 19861029; AR 31840990 A 19901119; AR 31841090 A 19901119; AT 86114748 T 19861023; AT 90101210 T 19861023; AU 6427786 A 19861022; CA 521561 A 19861028; CN 86107491 A 19861029; DE 10075028 C 19861023; DE 3650018 T 19861023; DE 3680859 T 19861023; DK 25992 A 19920228; DK 514586 A 19861028; EP 90101210 A 19861023; ES 86114748 T 19861023; ES 90101210 T 19861023; FI 864299 A 19861023; GE AP1993001276 A 19930729; GR 910401047 T 19910816; HU 447986 A 19861024; IL 8040486 A 19861023; JP 25717586 A 19861028; JP 35979491 A 19911226; KR 860009083 A 19861029; LU 88596 C 19861023; LU 90621 C 20000809; MY PI19860045 A 19861028; NL 300014 C 20000808; NL 970020 C 19970530; NO 864247 A 19861023; NZ 21808986 A 19861028; PH 34426 A 19861029; PT 8364386 A 19861029; SU 4203544 A 19871027; SU 4203548 A 19871027; US 92829786 A 19861028; YU 137191 A 19910808; YU 137291 A 19910808; YU 183586 A 19861029