EP 0222839 A4 19881109 - ANTIMALARIAL COMPOUNDS.
Title (en)
ANTIMALARIAL COMPOUNDS.
Title (de)
ANTIMALARIAVERBINDUNGEN.
Title (fr)
COMPOSES ANTIPALUDIQUES.
Publication
Application
Priority
- AU PH061385 A 19850517
- AU PH081985 A 19850530
Abstract (en)
[origin: WO8606718A1] Compounds of general formula (I) have antimalarial activity, wherein X represents a halogen or halogen-substituted alkyl group; Y represents CH or N; and R<1> and R<2>, which may be the same or different, represent hydrogen, aminoalkyl, mono- or di-alkylaminoalkyl, mono- or di-(substituted alkyl)aminoalkyl, mono- or di-(cycloalkyl)aminoalkyl, mono- or di-(aryl)aminoalkyl, mono- or di-(substituted aryl)aminoalkyl, or alkyl substituted by a nitrogen-containing heterocyclic or mono- or di-alkyl-substituted heterocyclic group; provided that R<1> and R<2> are not both hydrogen; and that R<2> is not diethylaminomethyl when X is chloro, Y is CH and R<1> is hydrogen; or when X is bromo, Y is N and R<1> is hydrogen. Processes for the preparation of these compounds are also disclosed.
IPC 1-7
IPC 8 full level
C07D 215/44 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
C07D 215/44 (2013.01); C07D 471/04 (2013.01)
Citation (search report)
- GB 612115 A 19481109 - PARKE DAVIS & CO
- See references of WO 8606718A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8606718 A1 19861120; EP 0222839 A1 19870527; EP 0222839 A4 19881109
DOCDB simple family (application)
AU 8600142 W 19860516; EP 86903140 A 19860516