EP 0223842 A4 19870824 - MONOCLONAL ANTIBODY TO DECAY ACCELERATING FACTOR (DAF), A METHOD FOR MAKING IT, AND USE.
Title (en)
MONOCLONAL ANTIBODY TO DECAY ACCELERATING FACTOR (DAF), A METHOD FOR MAKING IT, AND USE.
Title (de)
MONOKLONALER ANTIKÖRPER GEGEN ZERFALLAKZELERATIONSFAKTOR, DESSEN HERSTELLUNG UND VERWENDUNG.
Title (fr)
ANTICORPS MONOCLONAL DU FACTEUR D'ACCELERATION DE LA DECOMPOSITION (FAD), SON PROCEDE DE PRODUCTION ET D'UTILISATION.
Publication
Application
Priority
US 73817185 A 19850524
Abstract (en)
[origin: WO8607062A1] A monoclonal antibody immunochemically reactive with decay accelerating factor and a method for making such a monoclonal antibody by purifying decay accelerating factor to homogeneity by a combination of anion-exchange and hydrophobic interaction chromatography, gel filtration, lectin-Sepharose chromatography, immunoaffinity chromatography, anion exchange chromatography and high-performance liquid chromatography; immunizing mice with said purified factor; fusing spleen cells from said mice with mouse myeloma cells to produce hybrid cells; and screening said hybrid cells to identify those secreting said monoclonal antibody.
IPC 1-7
C07K 3/00; C12N 5/00; C12N 11/00; C12N 15/00; C12P 21/00; C12R 1/91; G01N 33/53; G01N 33/531; G01N 33/555
IPC 8 full level
A61K 39/00 (2006.01); C07K 1/20 (2006.01); C07K 1/22 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01); C07K 14/705 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12P 21/00 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
B82Y 5/00 (2013.01); C07K 14/705 (2013.01); C07K 16/2896 (2013.01); G01N 33/68 (2013.01); C07K 2319/035 (2013.01); C07K 2319/40 (2013.01); C07K 2319/75 (2013.01); G01N 2333/705 (2013.01)
Citation (search report)
- No relevant documents have been disclosed.
- See references of WO 8607062A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8607062 A1 19861204; EP 0223842 A1 19870603; EP 0223842 A4 19870824; JP S63500797 A 19880324
DOCDB simple family (application)
US 8601177 W 19860523; EP 86903931 A 19860523; JP 50331286 A 19860523