EP 0229165 A1 19870722 - VASO-OCCLUSIVE COLLAGEN COMPOSITION AND METHOD.
Title (en)
VASO-OCCLUSIVE COLLAGEN COMPOSITION AND METHOD.
Title (de)
VASO-OKKLUSIVE KOLLAGENZUSAMMENSETZUNG UND METHODE.
Title (fr)
PROCEDE ET COMPOSITION DE COLLAGENE VASO-OCCLUSIFS.
Publication
Application
Priority
- US 75160585 A 19850702
- US 82363586 A 19860129
Abstract (en)
[origin: WO8700062A1] A method and composition of achieving persistent occlusion of blood vessels, for a period of at least about two weeks. The method includes (a) providing a vaso-occlusive material composed of a suspension of atelopeptide collagen fibers which are cross-linked under conditions which raise the melting temperature of the suspension at least about 10<o>C, and (b) introducing the material into the blood vessels to be occluded. Also disclosed are novel methods which employ vaso-occlusion for enhancing hyperthermia and drug treatments, particularly of solid-tumor tissue.
Abstract (fr)
Un procédé et une composition permettent d'obtenir l'occlusion persistante de vaisseaux sanguins pendant au moins deux semaines environ. Le procédé comprend (a) la formation d'un matériau vaso-occlusif composé d'une suspension de fibres de collagène atélopeptide réticulées dans des conditions qui élèvent la température de fusion de la suspension d'au moins 10oC environ, et (b) l'introduction du matériau dans les vaisseaux sanguins que l'on veut occlure. Des procédés novateurs utilisent la vaso-occlusion pour favoriser l'hyperthermie et des traitements médicamenteux, en particulier de tissus porteurs de tumeurs solides.
IPC 1-7
IPC 8 full level
A61L 24/10 (2006.01); C07K 14/78 (2006.01); A61F 2/00 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61F 2/06 (2013.01); A61L 24/102 (2013.01); A61L 27/24 (2013.01); A61L 27/50 (2013.01); C07K 14/78 (2013.01); A61F 2310/00365 (2013.01); A61K 38/00 (2013.01); A61L 2430/36 (2013.01)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8700062 A1 19870115; AU 6129486 A 19870130; EP 0229165 A1 19870722; EP 0229165 A4 19880725
DOCDB simple family (application)
US 8601408 W 19860702; AU 6129486 A 19860702; EP 86904616 A 19860702