EP 0234524 B1 19940119 - Process for the detection of cancer using nuclear magnetic resonance.
Title (en)
Process for the detection of cancer using nuclear magnetic resonance.
Title (de)
Verfahren zum Nachweis von Krebs durch Anwendung von kernmagnetischer Resonanz.
Title (fr)
Procédé pour la détection du cancer utilisant la résonance magnétique nucléaire.
Publication
Application
Priority
US 83384086 A 19860226
Abstract (en)
[origin: EP0234524A2] A technique is disclosed for the detection of cancer using nuclear magnetic resonsance (NMR). Specifically, NMR parameters for protons of lipid methyl and/or methylene groups are determined and compared against a corresponding value for healthy patients. In the preferred embodiments, an NMR spectrometer is employed in conjunction with a Fourier transformer to provide a spectrum for non-water components of blood, blood serum or blood plasma and the width of the methyl and/or methylene groups is measured at half-height as a determination of spin-spin relaxation time (T2) which is the parameter used for purposes of comparison with healthy controls. Suppression of the water proton signal is employed where necessary in order to obtain a suitable spectrum for the non-water component protons.
IPC 1-7
IPC 8 full level
G01N 24/00 (2006.01); A61B 10/00 (2006.01); G01N 33/483 (2006.01); G01N 33/49 (2006.01); G01N 33/574 (2006.01); G01R 33/465 (2006.01); G01R 33/56 (2006.01); G01N 24/08 (2006.01)
CPC (source: EP)
G01R 33/465 (2013.01); G01R 33/56 (2013.01)
Citation (examination)
- CHEMICAL ABSTRACTS, vol. 81, no. 25, 23 December 1974, Columbus, OH (US); D.P. HOLLIS et al., p. 385, no. 167435e#
- CHEMICAL ABSTRACTS, vol. 101, no. 11, 10 September 1984, Columbus, OH (US); P.T. BEALL et al., p. 431, no. 88226r#
- CHEMICAL ABSTRACTS, vol. 105, no. 11, 15 September 1986, Columbus, OH (US); L.C. WRIGHT et al., p. 455, no. 95403g#
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0234524 A2 19870902; EP 0234524 A3 19890913; EP 0234524 B1 19940119; AT E100589 T1 19940215; AU 600931 B2 19900830; AU 6918987 A 19870827; BR 8700902 A 19871222; CA 1291532 C 19911029; CN 1012997 B 19910626; CN 87100925 A 19870930; DE 3788812 D1 19940303; DE 3788812 T2 19940505; DK 92187 A 19870827; DK 92187 D0 19870224; FI 870436 A0 19870202; FI 870436 A 19870827; IL 81276 A0 19870831; IL 81276 A 19910512; JP H0643995 B2 19940608; JP S62276459 A 19871201; NO 870780 D0 19870225; NO 870780 L 19870827
DOCDB simple family (application)
EP 87102435 A 19870220; AT 87102435 T 19870220; AU 6918987 A 19870224; BR 8700902 A 19870225; CA 530562 A 19870225; CN 87100925 A 19870225; DE 3788812 T 19870220; DK 92187 A 19870224; FI 870436 A 19870202; IL 8127687 A 19870115; JP 4665687 A 19870226; NO 870780 A 19870225