Global Patent Index - EP 0260635 A2

EP 0260635 A2 1988-03-23 - Electrophoresis-mass spectrometry probe.

Title (en)

Electrophoresis-mass spectrometry probe.

Title (de)

Sonde für Elektrophorese-Massenspektrometrie.

Title (fr)

Capteur à électrophorèse-spectrométrie à masses.

Publication

EP 0260635 A2 (EN)

Application

EP 87113397 A

Priority

US 90684786 A

Abstract (en)

The invention involves a new technique for the separation of complex mixtures of chemicals, which utilizes a unique interface probe for conventional mass spectrometers which allows the electrophoretically separated compounds to be analyzed in real-time by a mass spectrometer. This new chemical analysis interface,which couples electrophoresis with mass spectrometry, allows complex mixtures to be analyzed very rapidly, with much greater specificity, and with greater sensitivity. The interface or probe provides a means whereby large and/or polar molecules in complex mixtures to be completely characterized. The preferred embodiment of the probe utilizes a double capillary tip which allows the probe tip to be continually wetted by the buffer, which provides for increased heat dissipation,and results in a continually operating interface which is more durable and electronically stable than the illustrated single capillary tip probe interface.

IPC 1-7 (main, further and additional classification)

G01N 27/26; G01N 30/72; H01J 49/04

IPC 8 full level (invention and additional information)

G01N 27/62 (2006.01); G01N 27/447 (2006.01); H01J 49/04 (2006.01); H01J 49/14 (2006.01)

CPC (invention and additional information)

H01J 49/0431 (2013.01); G01N 27/44717 (2013.01); Y10T 436/24 (2013.01)

Designated contracting state (EPC)

DE FR GB SE

DOCDB simple family

US 4705616 A 19871110; DE 3789182 D1 19940407; DE 3789182 T2 19940929; EP 0260635 A2 19880323; EP 0260635 A3 19890823; EP 0260635 B1 19940302; JP 2572397 B2 19970116; JP S63154960 A 19880628