EP 0264091 B1 19920205 - 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE
Title (en)
3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE
Publication
Application
Priority
- JP 2186687 A 19870203
- JP 21923087 A 19870903
- JP 22214787 A 19870907
- JP 24148086 A 19861013
- JP 26279986 A 19861106
- JP 29257486 A 19861210
Abstract (en)
[origin: EP0264091A2] A 3-propenylcephem derivative of the following formula: <CHEM> wherein R1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcehem derivative; and Process for the preparation of the intermediate.
IPC 1-7
IPC 8 full level
A61K 31/545 (2006.01); A61K 31/546 (2006.01); C07D 285/08 (2006.01); C07D 501/00 (2006.01); C07D 501/04 (2006.01); C07D 501/24 (2006.01); C07D 501/46 (2006.01); C07D 501/56 (2006.01); C07D 519/00 (2006.01)
IPC 8 main group level
C07D (2006.01)
CPC (source: EP US)
C07D 501/24 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0264091 A2 19880420; EP 0264091 A3 19891227; EP 0264091 B1 19920205; CA 1290748 C 19911015; CN 1020104 C 19930317; CN 87107610 A 19880601; DE 3776620 D1 19920319; DK 174995 B1 20040413; DK 531387 A 19880414; DK 531387 D0 19871012; ES 2039223 T3 19930916; FI 874492 A0 19871012; FI 874492 A 19880414; FI 89169 B 19930514; FI 89169 C 19930825; GR 3003841 T3 19930316; HU 207088 B 19930301; HU T47119 A 19890130; IL 84128 A0 19880331; IL 84128 A 19921201; NO 170021 B 19920525; NO 170021 C 19920902; NO 874255 D0 19871012; NO 874255 L 19880414; NZ 222116 A 19900828; PT 85906 A 19871101; PT 85906 B 19900831; US 4921850 A 19900501; US 5006649 A 19910409; US 5066812 A 19911119; US 5089491 A 19920218
DOCDB simple family (application)
EP 87114843 A 19871012; CA 548948 A 19871009; CN 87107610 A 19871012; DE 3776620 T 19871012; DK 531387 A 19871012; ES 87114843 T 19871012; FI 874492 A 19871012; GR 910402077 T 19920219; HU 459987 A 19871012; IL 8412887 A 19871007; NO 874255 A 19871012; NZ 22211687 A 19871009; PT 8590687 A 19871012; US 10763187 A 19871013; US 46351490 A 19900111; US 46351890 A 19900111; US 46351990 A 19900111