EP 0269677 A4 19900308 - ASSAYS AND ANTIBODIES FOR N--i(myc) PROTEINS.

Title (en)

ASSAYS AND ANTIBODIES FOR N--i(myc) PROTEINS.

Title (de)

TESTVERFAHREN UND ANTIKÖRPER FÜR N-MYC-PROTEINE.

Title (fr)

ANALYSES ET ANTICORPS DES PROTEINES N--i(myc).

Publication

EP 0269677 A4 19900308 (EN)

Application

EP 87903573 A 19870505

Priority

US 86027686 A 19860506

Abstract (en)

[origin: WO8706940A1] Methods and compositions for identifying patients suffering from cancer, particularly neural and neuroendocrine cancers. It has been found that the protein expression product of the human N-myc photo-oncogene may be detected in certain biological specimens, particularly tissue specimens and sputum samples. By obtaining immunogenic N-myc polypeptides, either synthetically or by isolation from a natural source, antibodies specific for the N-myc protein are obtained. Those antibodies may then be used in immunological techniques for detecting the presence of N-myc in the biological samples. In particular, the antibodies may be employed in immunohistochemical techniques to detect the N-myc protein in prepared tissue and sputum samples.

IPC 1-7

C07K 7/06; C07K 7/08; C07K 7/10; C07K 15/12; A61K 39/395; G01N 33/53; C12N 15/00

IPC 8 full level

C12P 21/02 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07H 21/04 (2006.01); C07K 1/22 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/82 (2006.01); C07K 16/00 (2006.01); C07K 16/32 (2006.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

C07K 14/82 (2013.01); C07K 16/32 (2013.01); G01N 33/5748 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

[E] EP 0318179 A2 19890531 - PROGENX INC [US]
[X] WO 8500807 A1 19850228 - SCRIPPS CLINIC RES [US]
See references of WO 8706940A1

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 8706940 A1 19871119; AU 596670 B2 19900510; AU 7480387 A 19871201; EP 0269677 A1 19880608; EP 0269677 A4 19900308; JP 2726264 B2 19980311; JP H01501518 A 19890601

DOCDB simple family (application)

US 8701046 W 19870505; AU 7480387 A 19870505; EP 87903573 A 19870505; JP 50321887 A 19870505