EP 0271521 A4 19891114 - LIPOPOLYSACCHARIDE AND NATURAL FACTOR COMPOSITIONS FOR ANTI-TUMOR THERAPY AND METHOD OF TREATMENT.
Title (en)
LIPOPOLYSACCHARIDE AND NATURAL FACTOR COMPOSITIONS FOR ANTI-TUMOR THERAPY AND METHOD OF TREATMENT.
Title (de)
ZUBEREITUNGEN VON LIPOPOLYSACCHARIDEN UND NATÜRLICHEM FAKTOR ZUR ANTITUMORTHERAPIE UND VERFAHREN ZUR BEHANDLUNG.
Title (fr)
COMPOSITIONS A BASE DE LIPOPOLYSACCHARIDES ET DE FACTEURS NATURELS DANS LA THERAPIE ANTITUMORALE ET PROCEDE DE TRAITEMENT.
Publication
Application
Priority
US 86156686 A 19860509
Abstract (en)
[origin: WO8706830A1] Bacterial lipopolysaccharide (LPS) can be used to induce release of factors into the serum enabling rejection of tumors and increasing the efficacy of added anti-tumor agents. Thus exogenous TNF, when used together with LPS or other factors induced by LPS can be used at lower non-toxic doses to cause tumor rejection. These factors can be combined in anti-tumor therapy with other chemotherapeutic agents such as indomethacin or cyclophosphamide or natural agents such as platelet factor 4 which block negative feedback responses suppressing the immune system, thereby mediating the body resistance to the therapy.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 31/715 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01)
CPC (source: EP)
A61K 31/405 (2013.01); A61K 31/675 (2013.01); A61K 31/715 (2013.01); A61K 38/191 (2013.01); A61K 38/195 (2013.01); A61K 38/2006 (2013.01); A61K 38/2013 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01)
Citation (search report)
- No further relevant documents have been disclosed.
- See references of WO 8706830A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8706830 A1 19871119; AU 7397887 A 19871201; EP 0271521 A1 19880622; EP 0271521 A4 19891114; JP S63503308 A 19881202
DOCDB simple family (application)
US 8701050 W 19870507; AU 7397887 A 19870507; EP 87903576 A 19870507; JP 50303187 A 19870507