Title (en)

SUBSTITUTED 3-PHENYL-7H-THIAZOLO(3,2-B)(1,2,4)TRIAZIN-7-ONES, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS WELL AS SOME OF THE INTERMEDIATES OBTAINED DURING THE PREPARATION OF SAID COMPOUNDS

Publication

EP 0276805 B1 19930317 (DE)

Application

EP 88101057 A 19880126

Priority

DE 3702758 A 19870130

Abstract (en)

[origin: US4908364A] Novel substituted 3-phenyl-7H-thiazolo[3,2-b][1,2,4]-triazin-7-ones of the formula I are disclosed <IMAGE> (I) in which R1, R2 and R3 have the meaning recited in the specification. The compounds are suitable for prevention and treatment of inflammatory disorders.

IPC 1-7

A61K 31/53; C07D 253/06; C07D 513/04

IPC 8 full level

A61K 31/53 (2006.01); A61P 29/00 (2006.01); C07D 253/06 (2006.01); C07D 253/075 (2006.01); C07D 285/16 (2006.01); C07D 513/04 (2006.01)

CPC (source: EP US)

A61P 29/00 (2017.12 - EP); C07D 253/075 (2013.01 - EP US); C07D 285/16 (2013.01 - EP US); C07D 513/04 (2013.01 - EP US)

Citation (examination)

• EP 0164765 A1 19851218 - YAMANOUCHI PHARMA CO LTD [JP]
• CHEMICAL ABSTRACTS, Band 92, Nr. 9, 3. März 1980, Seite 676, Zusammenfassung-Nr. 76459b, Columbus, Ohio, US; E.S.A. IBRAHIM et al.: "Potential antineoplastics. Part 2. New thiazolo[1,2,4]triazine derivatives"
• CHEMICAL ABSTRACTS, Band 68, Nr. 7, 12. Februar 1968, Seiten 2883-2884, Zusammenfassung-Nr. 29682p, Columbus, Ohio, US; G. DOLESCHALL et al.: "1,2,4-triazines and condensed derivatives. III. The synthesis of some 7H-thiaziolo[3,2-b]-1,2,4-triazin-7-ones"
• PATENT ABSTRACTS OF JAPAN, Band 8, Nr. 106 (C-223) [1543], 18. Mai 1984; SUMITOMO KAGAKU KOGYO K.K.: "4-allyl-1,2,4-triazin-5(2H)-one-3-thione derivative and its preparation"
• CHEMICAL ABSTRACTS, Band 104, Nr. 7, 17. Februar 1986, Seite 513, Zusammenfassung-Nr. 50789a, Columbus, Ohio, US; TEIKOKU HORMONE MFG. CO., LTD.: "3-substituted-2-phenylindole derivatives"
• CHEMICAL ABSTRACTS, Band 90, Nr. 15, 09. April 1979, Seite 28, Zusammenfassung-Nr. 114920p, Columbus, Ohio, US; H. VAN DER GOOT et al.: "The synthesis and anti-inflammatory activity of substituted 2-(4-hydroxyphenyl)-1,3-indandiones"
• CHEMICAL ABSTRACTS, Band 82, Nr. 9, 03. September 1975, Seite 579, Zusammenfassung-Nr. 57744t, Columbus, Ohio, US; N. YOSHIDA et al.: "2-amino-1,3,4-thiadiazine derivatives"
• CHEMICAL ABSTRACTS, Band 85, Nr. 23, 06. Dezember 1978, Seite 521, Zusammenfassung-Nr. 177376h, Columbus, Ohio, US; I.YA. POSTOVSKII et al.: "Synthesis of 2-hydrazino- and 2-amino-1,3,4-thiadiazines containing residues of polyhydric phenols in position 5"

Designated contracting state (EPC)

AT BE CH DE ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

EP 0276805 A2 19880803; EP 0276805 A3 19890322; EP 0276805 B1 19930317; AT E87002 T1 19930415; AU 1099688 A 19880811; AU 600080 B2 19900802; CA 1317293 C 19930504; CN 88100518 A 19880810; CS 268194 B2 19900314; CS 53688 A2 19890414; DD 287506 A5 19910228; DE 3702758 A1 19880929; DE 3879234 D1 19930422; DK 47988 A 19880731; DK 47988 D0 19880129; ES 2053590 T3 19940801; FI 880385 A0 19880128; FI 880385 A 19880731; HU 197752 B 19890529; HU T46921 A 19881228; IE 880246 L 19880730; IL 85231 A0 19880731; JP H07626 B2 19950111; JP S63192782 A 19880810; MX 10256 A 19931101; NO 880405 D0 19880129; NO 880405 L 19880801; NZ 223333 A 19890829; PH 24501 A 19900718; PT 86654 A 19880201; PT 86654 B 19920228; SU 1579462 A3 19900715; SU 1591808 A3 19900907; US 4908364 A 19900313; ZA 88639 B 19881026

DOCDB simple family (application)

EP 88101057 A 19880126; AT 88101057 T 19880126; AU 1099688 A 19880129; CA 557744 A 19880129; CN 88100518 A 19880129; CS 53688 A 19880128; DD 31251588 A 19880128; DE 3702758 A 19870130; DE 3879234 T 19880126; DK 47988 A 19880129; ES 88101057 T 19880126; FI 880385 A 19880128; HU 39188 A 19880128; IE 24688 A 19880129; IL 8523188 A 19880128; JP 1751288 A 19880129; MX 1025689 A 19890129; NO 880405 A 19880129; NZ 22333388 A 19880128; PH 36420 A 19880128; PT 8665488 A 19880128; SU 4355085 A 19880129; SU 4356771 A 19881109; US 14960388 A 19880128; ZA 88639 A 19880129